# Botswana-Harvard T.H. Chan School of Public Health AIDS Initiative Partnership CTU Y18 Supplement

> **NIH NIH UM1** · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · 2024 · $79,898

## Abstract

Project Summary/Abstract
The Clinical Trials Unit (CTU) in Botswana conducts research related to adult and pediatric HIV
therapeutic strategies; interventions to address HIV-associated infections/conditions in pediatric and
maternal populations; treatment and prevention of tuberculosis in adults (including pregnant women) and
children with and without HIV; and integrated HIV prevention strategies in pediatric and adult
populations.
These activities occur through participation in three research networks: 1) the ACTG; 2) IMPAACT, and
3) HPTN. We perform multi-center studies at our two established CRSs: one in Gaborone (all 3
networks), the capital city of Botswana, and the other in Molepolole (IMPAACT network only), the largest
village in Botswana. We thus work with both urban and village populations of all ages and of both sexes.
The primary objective of this CTU project in Botswana is to participate in and and contribute to the
following high-impact areas of research:
• Novel and durable treatments for HIV in adults (including pregnant women) and children
• Strategies to induce ART-free HIV remission (or eradication) in adults and children
• Treatment and prevention of HIV-related complications and co-infections in adults and children
• New treatments / modalities and prevention approaches for tuberculosis in adults and children
• HIV prevention strategies, including pre-exposure prophylaxis and integrated prevention approaches
Within each of these research areas, this CTU will contribute significantly to:
• Enrolling participants into and conducting high-quality clinical research studies,
• Participating in network activities, including protocol teams and scientific / resource committees, and
• Conceiving and proposing new, relevant, high-impact studies in priority areas

## Key facts

- **NIH application ID:** 11069349
- **Project number:** 3UM1AI069456-18S1
- **Recipient organization:** HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH
- **Principal Investigator:** SHAHIN LOCKMAN
- **Activity code:** UM1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $79,898
- **Award type:** 3
- **Project period:** 2024-07-05 → 2024-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11069349

## Citation

> US National Institutes of Health, RePORTER application 11069349, Botswana-Harvard T.H. Chan School of Public Health AIDS Initiative Partnership CTU Y18 Supplement (3UM1AI069456-18S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/11069349. Licensed CC0.

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