Project Summary/Abstract EJH & Associates, LLC (dba Datastream Connexion), propose the continuing development and operations of a Vet-LIRN portal based on a collaborative suite of online tools called LABSuite, which includes laboratory specific technology and functions. This is the current implementation of the Vet-LIRN portal and has successfully facilitated Vet-LIRN needs over the previous project period. Capabilities include customized working groups, web-based proficiency testing registration and management, and tools that support secure information sharing among animal health and veterinary diagnostic stakeholders. Collectively, the LABSuite & GovSuite combined platform tools is a sustainable model built and operationalized for secure communication, coordination, collaboration, education, and training among stakeholders charged with protecting the nation's critical infrastructures such as food and agriculture. This proposal focuses on two main objectives: 1. Advance tools that currently operate the technology needs of the Veterinary Laboratory Investigation and Response Network (Vet- LIRN) laboratories’ capacity to respond to animal food/drug related contamination through efficient online data capture and management of laboratory capabilities and proficiency testing results. 2. Facilitate secure information sharing and communication for enhanced animal and public health. LABSuite tools allow professionals working in different organizations (e.g. government, academia) to work together on essential missions and responsibilities despite differences in authorities, objectives, and roles. This robust platform connects the community stakeholders to a centralized online environment and houses databases of current information related to the mission of the Vet-LIRN to include but not limited to laboratory testing protocols, facilities, equipment and professional expertise and contacts. Current LABSuite Information Sharing Environments (ISEs) include the Food Emergency Response Network (FERN- https://www.fernlab.org) and the APHIS Laboratory Portal (https://www.nahln.org), formerly called the National Animal Laboratory Network Portal. The work is critical as FDA monitors the capability and performance of state, and university animal diagnostic laboratories to respond to threats; from past intentional melamine contamination in pet food to emerging antimicrobial resistance of bacterial pathogens.