Project Summary/Abstract This is a request for a supplement to our parent grant, “BioPortal: An expansive knowledgebase of biomedical entities and relations.” The supplement would allow us to replace the obsolete server system that provides storage for the more than 1000 publicly accessible biomedical ontologies managed by BioPortal. The BioPortal system provides access to nearly all the world’s publicly available biomedical ontologies and controlled terminologies, and it is used extensively by many secondary resources that are important to the NIH, including the CEDAR metadata management system and the REDCap system for electronic data capture. Our parent grant supports continued maintenance of BioPortal and the development of new features that are important to the biomedical community. Our ongoing work is threatened because the hardware that provides storage of BioPortal ontologies has already reached the end of its anticipated lifespan and is beginning to show signs of failure. We therefore wish to replace the existing server system with modern equipment with an extended period of performance. This singular equipment purchase will enhance access to BioPortal, ensure that we are able to continue to extend the capabilities of the BioPortal resource, and enable us to fulfill the specific aims of our parent grant without fear of server failures. BioPortal is the world’s most widely accessed knowledge base of biomedical concepts and relationships. The availability of this new equipment will support both our enormous user community and the scientific goals of our parent award.