EXposomic Profiling in Airway disease to uNravel Determinants of disease in Asthma (EXPAND-Asthma) Center

NIH RePORTER · NIH · U01 · $80,575 · view on reporter.nih.gov ↗

Abstract

Project Summary/Abstract This supplement aims to support Sally Guan for two years prior to graduate school matriculation to help her build a strong foundation grounded in mixed methods research and achieve her career goals of becoming a scientific researcher who studies the intersections between climate change, environmental justice, and community health. This research fellowship will provide Sally with an opportunity to develop the fundamental skills to prepare her to conduct her own independent research. Under the guidance of Dr. Neeta Thakur, Sally will estimate indoor infiltration of outdoor fine particulate matter (PM2.5) and will be investigating housing quality as an important modifiable target for augmenting exposure to outdoor air pollution for children with asthma. Sally will contribute to the EXposomic Profiling in Airway disease to uNravel Determinants of disease (EXPAND) Asthma study. It is known that social stressors and environmental exposures are strongly associated with asthma morbidity, and this relationship disproportionately affects communities of color. To best understand this relationship, UCSF is working with LifeLong Jenkins Health Center to help recruit children and adolescents, ages 8-16 years, with and without asthma to participate in the study. Sally’s role would be to estimate the infiltration factor in the homes included in the EXPAND study. Participants in the study will have a purple air monitor in the homes to capture spatial and temporal trends — specifically PM2.5. Sally will also use a qualitative method to further understand the barriers to access to retrofits and weatherization for those participating in the study.

Key facts

NIH application ID
11090180
Project number
3U01HG013276-02S1
Recipient
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
Principal Investigator
Stephanie A Christenson
Activity code
U01
Funding institute
NIH
Fiscal year
2024
Award amount
$80,575
Award type
3
Project period
2023-09-12 → 2028-05-31