# The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areas

> **NIH NIH P51** · TEXAS BIOMEDICAL RESEARCH INSTITUTE · 2024 · $496,000

## Abstract

Project Summary
There remains an acute, critical need to study HIV/AIDS as approximately 32,000 individuals are infected
annually in the U.S. and mortality globally remains at over 630,000 annually. The NIH Office of AIDS has four
main priority areas for HIV/AIDS research: reduce the incidence, develop HIV cures, develop next generation
therapies and address HIV comorbidities. The National Primate Research Centers are charged with supporting
the national needs for nonhuman primate research, with a significant priority on supporting HIV/AIDS related
research. The Southwest National Primate Research Center (SNRPC) actively supports research projects in
each of the priority areas designated by the Office of AIDS research.
There remains a current shortage of Indian origin rhesus macaques in the U.S. due to a ban on exportation and
recent global pressures significantly exacerbating the supply. This has led to the increased demand for P51
supported animals to be used to supply HIV/AIDS projects. The SNPRC has been disproportionately affected by
the national macaque shortage due to the small size of our SPF rhesus colony and the assumption of a greater
responsibility for research using rhesus. The SNPRC resources serve not only a number of internal core
scientists that are focused on infectious disease, but also a heavily external-facing research portfolio. The
SNPRC supports > 230 active research requests from > 120 affiliated scientists, with >30 % of rhesus macaque
projects completed onsite associated with HIV/AIDS related research. These requests have increased the
demand for appropriate ABSL2 research holding space in order to support the upcoming HIV/AIDS related
projects.
This proposed P51 supplement will meet an urgent need to upgrade ABSL2 macaque holding space to support
HIV/AIDS related research. Over the last decade several ABSL2 buildings and rooms have been removed from
service and taken offline at SNPRC due to failing HVAC systems. This supplement will provide HVAC upgrades
to eight ABSL2 rooms to bring them back into service to support rhesus macaque holding at SNPRC.

## Key facts

- **NIH application ID:** 11093857
- **Project number:** 3P51OD011133-26S1
- **Recipient organization:** TEXAS BIOMEDICAL RESEARCH INSTITUTE
- **Principal Investigator:** Larry S. Schlesinger
- **Activity code:** P51 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $496,000
- **Award type:** 3
- **Project period:** 2024-07-01 → 2025-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11093857

## Citation

> US National Institutes of Health, RePORTER application 11093857, The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areas (3P51OD011133-26S1). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/11093857. Licensed CC0.

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