Project Abstract We request supplemental support for the purchase of a “Micro Clima-Series™ Premium ICH Insect Chamber” from Snijders Labs to further the research capacity of the MVP lab. This machine has unique and specific features that will allow for in-depth investigation on the impact of environmental conditions on mosquito development, adaptation, vectorial capacity, and adult mosquito mating and feeding behaviors. It will enable us to simulate diverse and dynamic diurnal environments with precise changes in temperature, humidity, and lighting. We propose three scientific aims that the “Micro Clima-Series™ Premium ICH Insect Chamber” will enable our research program to investigate: - Aim 1: Vectorial capacity of mosquito vectors in the lens of the five IPCC climate change scenarios. - Aim 2: Adaptations of a tropical mosquito vector, Aedes aegypti, in cooler climates of North America. - Aim 3: Optimizing male mosquito fitness for Sterile Insect Technique. These aims fall within the scope of the parent award to perform high quality research on disease-transmitting mosquitoes, educate future leaders in the field of vector biology, and develop novel methods for mosquito control.