# Regulation of OATP1B1 and OATP1B3 by lysine acetylation and lysine deacetylase inhibitors

> **NIH NIH R01** · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · 2024 · $96,071

## Abstract

The goal of this application is to request funding to purchase the Jess System from ProteinSimple
for automated quantitative protein analysis. The Jess system is a capillary-based Western system
that is gel free and blot free and which fully automates loading, size-based protein separation,
data analysis and antibody probing, washing and detection. The Jess System executes protein
analysis with high sensitivity, exceptional reproducibility, accurate protein quantification and rapid
and high-throughput capabilities. Incorporating the Jess System into my research will improve my
research program, enhance the Rigor and Reproducibility for studies outlined in the parental R01
award. Additionally, the Jess System will facilitate adherence to the data sharing policy of NIH.

## Key facts

- **NIH application ID:** 11100469
- **Project number:** 3R01GM146956-03S1
- **Recipient organization:** UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
- **Principal Investigator:** Wei Yue
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $96,071
- **Award type:** 3
- **Project period:** 2022-09-01 → 2026-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11100469

## Citation

> US National Institutes of Health, RePORTER application 11100469, Regulation of OATP1B1 and OATP1B3 by lysine acetylation and lysine deacetylase inhibitors (3R01GM146956-03S1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/11100469. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*