The Pittsburgh Center for Training in Kidney, Urology and Hematology (PCT-KUH) is designed to prepare predoctoral students, MDs and PhDs for biomedical research careers by providing a concentrated, in-depth research experience. This program is designed to foster a rigorous approach to scientific inquiry in basic, translational or clinical investigation. Our seventy-four training program faculty are members of the University of Pittsburgh and Carnegie Mellon University. Together they form a well-integrated and collaborative entity dedicated to research training and investigation in nephrology, benign urology and benign hematology. Trainees are recruited from divisions and departments at the University of Pittsburgh, Carnegie Mellon University and the Allegheny Health System. They will develop research projects under the supervision of faculty trainers and will be closely monitored and evaluated by an advisory committee, career advisors and by our research training executive committee. Didactic lectures, research seminars, journal clubs, formal course work, attendance at scientific meetings, professional development programs and networking opportunities supplement an intensively structured research experience. Predoctoral graduates of this comprehensive training experience will be equipped to compete for individual training support. Postdoctoral graduates of this program will be prepared to compete for independent funding and entry-level faculty positions in academic medicine or industry.