ADMINISTRATIVE CORE SUMMARY The Administrative Core will be responsible for program coordination, communication with outside entities, and fiscal management. The core will be led by the PI, Dr. David Erle, who has substantial experience with leading large NIH-funded multi-investigator programs. The Administrative Core will coordinate activities of the two projects and the Clinical Subject and Biospecimen Processing and Analysis Core to ensure that critical information and biospecimens are shared efficiently. The Administrative Core will arrange monthly AADCRC conferences and meetings with the internal advisory committee and external advisors. We will continue to seek opportunities to use AADCRC infrastructure and opportunity funds to support a diverse group of early-stage investigators working to establish careers related to asthma and allergic diseases and to support collaborations with other AADCRCs. The PI will participate in monthly conference calls with NIAID staff and leaders of other AADCRCs and will work with other program personnel to ensure we are well-represented at the annual AADCRC meetings in Bethesda. The PI will work closely with an experienced administrative staff member to ensure that AADCRC funds are spent wisely and according to all applicable NIH regulations.