# Administrative Core

> **NIH NIH U19** · FRED HUTCHINSON CANCER CENTER · 2024 · $814,513

## Abstract

PROJECT SUMMARY/ABSTRACT
The Administrative Core will provide a strong infrastructure as well as administrative and logistical support to 
ensure timely implementation of all Projects, Core activities, and cross-project collaborative opportunities for the 
CANOE Partnership: Cancer Awareness, Navigation, Outreach, and Equitable Indigenous Health Outcomes. 
The three Projects will have geographic diversity, which adds to the complexity of the overall U19 proposal and 
requires the experienced Administrative Core leadership team to ensure application of the Indigenous Cancer 
Health Equity-Initiative (ICHE-i) Model in the design and implementation of Projects and Cores. They will also
implement the overall evaluation plan using the Indigenous Evaluation Framework. The Administrative Core 
leaders, Drs. Lonnie Nelson, Myra Parker, and Jason “Jay” Mendoza are the MPIs of the CANOE Partnership 
and have extensive experience leading research projects with Indigenous populations and applying CBPR 
approaches in their work. The Specific Aims include:
1) Design and support the overall program structure and goals using the ICHE-i Model, which centers 
relationality, a holistic approach, and sustainability in support of Tribal Sovereignty as integral to TribalAcademic research partnerships. 
2) Apply an Indigenous Evaluation Framework to assess program milestones and outcomes using a mixed 
methods approach that triangulates quantitative and qualitative data. The Framework will inform tracking of 
Project and Core milestones and evaluations; bidirectionality of equitable research processes; and collection 
of Indigenous Success Measures as empirical, revealed, and traditional knowledge types.
3) Facilitate and harmonize the use of common data elements across research projects and provide a 
biostatistical resource to conduct each Project’s data analyses. We will use a collection of tools extracted 
from the PhenX Toolkit to assess social determinants of health (SDOH) and other predictors of Project 
outcomes across all CANOE Partnership Projects and data collection activities. Where needed, measures 
will undergo cultural adaptation for Indigenous populations using a process that considers eight dimensions 
of culture.
Impact: The Administrative Core will be led by three experienced MPIs who are supported by key staff leaders 
with substantial expertise administering research grants as collaborations with AI/AN participants. Altogether 
they will lead an efficient operations and oversight infrastructure that will enable the Research Project 
investigators, staff, and Tribal Organizations/Tribes to equitably and bidirectionally implement the three proposed 
Research Projects to address cancer inequities nationally (smoking cessation) and in our Washington state 
catchment area (lung, breast, and colorectal cancer screenings and HPV vaccinations).

## Key facts

- **NIH application ID:** 11160295
- **Project number:** 1U19MD020533-01
- **Recipient organization:** FRED HUTCHINSON CANCER CENTER
- **Principal Investigator:** Jason A Mendoza
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $814,513
- **Award type:** 1
- **Project period:** 2024-09-21 → 2029-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11160295

## Citation

> US National Institutes of Health, RePORTER application 11160295, Administrative Core (1U19MD020533-01). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/11160295. Licensed CC0.

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