# An Easy-to-Use, Low-Cost Triplex RDT for the Simultaneous Diagnosis of HBV, HCV, AND HIV Infection, Compatible with Field Use in LMICS and At-Home Use in the US

> **NIH NIH N43** · BIG EYE DIAGNOSTICS, INC. · 2024 · $299,659

## Abstract

Multiplexed Patient Administered Diagnostics for Hepatitis B, Hepatitis C, and HIV: HIV and viral hepatitis infections share common modes of transmission and social and structural barriers to accessing care and services among key populations. Coinfection with HIV significantly impacts the pathogenesis of HBV and HCV and is associated with reduced spontaneous clearance of HCV and HBsAg, higher rates of chronicity and occult HBV, higher HCV viral loads, rapid disease progression, and increased risk of morbidity and mortality due to cirrhosis and HCC. Integrated strategies for screening and diagnosis of HIV and viral hepatitis infections are therefore critical to an effective global health response. This contract aims to to develop mono-plex prototypes of a patient administered diagnostic test for HBV, HCV, and HIV using antibody detection in a lateral flow assay.

## Key facts

- **NIH application ID:** 11170172
- **Project number:** 75N93024C00025-0-9999-1
- **Recipient organization:** BIG EYE DIAGNOSTICS, INC.
- **Principal Investigator:** Marco Antonio Biamonte
- **Activity code:** N43 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $299,659
- **Award type:** —
- **Project period:** 2024-08-01 → 2025-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11170172

## Citation

> US National Institutes of Health, RePORTER application 11170172, An Easy-to-Use, Low-Cost Triplex RDT for the Simultaneous Diagnosis of HBV, HCV, AND HIV Infection, Compatible with Field Use in LMICS and At-Home Use in the US (75N93024C00025-0-9999-1). Retrieved via AI Analytics 2026-09-07 from https://api.ai-analytics.org/grant/nih/11170172. Licensed CC0.

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