# Southeast Enrollment Center Consortium 2 (SEEC-2)

> **NIH NIH OT2** · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · 2024 · $1,250,000

## Abstract

The All Of Us Research Program (AOURP) is a historic effort to enable 21st century biomedical 
research that will benefit all persons in the USA. The inclusion of at least 1 million volunteers into 
one study is not only unprecedented in scale, but also sets new standards in reaching every
individual, regardless of race and ethnicity, age, geography, or health status. This will power 
genetic studies of health and well-being, which will eventually deliver more precise treatments 
and personalized medications. Already, early examples of this approach are apparent in the form 
of advanced cancer treatments and genetic therapies. Large and easily accessible datasets are 
essential to support the research needed for such breakthrough advances. In return, AOURP 
participants will have access to their genetic data, receive medically relevant personalized 
feedback, and gain insights into other aspects of their own personal health. A specific strength of 
the AOURP is the role of Regional Medical Centers (RMC), which provide their experienced staff 
and faculty, their resources, and their trusted relationships with patients and communities, to 
engage, enroll, and retain participants for the AOURP study. We have formed a consortium of such RMCs in the States of Florida, Georgia, and the Territory of Puerto Rico. We call this the SouthEast Enrollment Center (SEEC-2), led by University of Miami, University of Florida 
Gainesville, Morehouse School of Medicine, Emory University, and the University of Puerto Rico 
Comprehensive Cancer Center. These five prestigious academic regional medical centers are 
further allied with several public and private hospital systems and are working with dozens of 
regional partner organization to allow every individual in this geographic area access to the 
AOURP. Over the past five years, the SEEC team has registered more than 51,000 individuals 
and fully enrolled nearly 40,000 core participants into the AOURP study. At a closer look, 
these participants truly represent the diversity of people living in this region. More than 67% 
identify with a race or ethnicity that is historically not well represented in medical research 
studies, thus potentially missing out on the benefits of new treatments. Approximately 25% are of 
older age, and 18% have disabilities; together 93% of SEEC participants belong to the category 
of Underrepresented in Biomedical Research (UBR). More than 44% of SEEC enrolled 
participants have actively followed up with the Program after their initial enrollment activities.
The next phase, SEEC-2, will help push the national participant count to over 1 million AOURP 
individuals. We will more than double the above engagement and enrollment numbers, make 
AOURP a well-known mainstay in our communities, retain the majority of core participants, and 
foster the adoption of the researcher workbench. We plan to significantly expand our enrollment 
options and to implement novel activities, in order to make...

## Key facts

- **NIH application ID:** 11193592
- **Project number:** 3OT2OD037907-01S1
- **Recipient organization:** UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
- **Principal Investigator:** Jacob L McCauley
- **Activity code:** OT2 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $1,250,000
- **Award type:** 3
- **Project period:** 2024-09-24 → 2026-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11193592

## Citation

> US National Institutes of Health, RePORTER application 11193592, Southeast Enrollment Center Consortium 2 (SEEC-2) (3OT2OD037907-01S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/11193592. Licensed CC0.

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