# TIME-RESTRICTED FEEDING FOR PANCREATIC CANCER PREVENTION

> **NIH NIH N01** · UNIVERSITY OF TX MD ANDERSON CAN CTR · 2024 · $551,730

## Abstract

The overarching goal of this Task Order is to determine the efficacy of time-restricted feeding (TRF) on PanIN prevention in a mouse model of pancreatic cancer and identify efficacy
biomarkers. The preliminary results suggest fasting regimens are feasible and safe interventions which can
modulate PDAC tumor growth, immune infiltration and microbiome composition. Short-term and long-term TRF
interventions will be conducted to study PanIN progression and PDAC development in KC mice in order to
identify and validate non-invasive biomarkers of treatment efficacy.

## Key facts

- **NIH application ID:** 11193654
- **Project number:** 75N91024D00004-0-759102400002-1
- **Recipient organization:** UNIVERSITY OF TX MD ANDERSON CAN CTR
- **Principal Investigator:** Eduardo Vilar Sanchez
- **Activity code:** N01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $551,730
- **Award type:** —
- **Project period:** 2024-09-20 → 2026-03-19

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11193654

## Citation

> US National Institutes of Health, RePORTER application 11193654, TIME-RESTRICTED FEEDING FOR PANCREATIC CANCER PREVENTION (75N91024D00004-0-759102400002-1). Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/grant/nih/11193654. Licensed CC0.

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