# Functional B-cell Epitope Discovery for Arthropod-Borne Diseases

> **NIH NIH N01** · WASHINGTON UNIVERSITY · 2024 · $1,794,234

## Abstract

The primary goal of this proposal is the delineation of functional B cell epitopes recognized by potently neutralizing or protective antibodies to facilitate future development of safe and effective vaccines and therapeutics. A second major goal of this project is the
development of correlates relating B cell epitopes with mAb neutralization potency and protection in mouse models of infection. This proposal will focus on arthropod-transmitted flaviviruses and alphaviruses.

## Key facts

- **NIH application ID:** 11196675
- **Project number:** 75N93024C00070-0-9999-1
- **Recipient organization:** WASHINGTON UNIVERSITY
- **Principal Investigator:** —
- **Activity code:** N01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $1,794,234
- **Award type:** —
- **Project period:** 2024-09-16 → 2025-09-15

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11196675

## Citation

> US National Institutes of Health, RePORTER application 11196675, Functional B-cell Epitope Discovery for Arthropod-Borne Diseases (75N93024C00070-0-9999-1). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/11196675. Licensed CC0.

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