# NIMH SYNTHESIS AND DISTRIBUTION OF DRUGS OF ABUSE AND RELATED COMPOUNDS. JUNE 16, 2024 - JUNE 15, 2025. TASK ORDER 75N95024F00002 (TO7). N01DA-22-8944.

> **NIH NIH N01** · RESEARCH TRIANGLE INSTITUTE · 2024 · $376,358

## Abstract

The purpose of the NIMH Chemical Synthesis and Drug Supply Program is to synthesize, purify, and provide essential compounds that are unavailable from commercial sources (e.g., the stock has been depleted and it will not be replenished, patented compounds that are unavailable while undergoing clinical trials, etc.) to stimulate basic and clinical research relevant to mental health in areas such as the molecular pharmacology and signaling of CNS receptors, longitudinal studies to evaluate the molecular, biochemical, and behavioral actions of psychoactive compounds, and functional brain imaging in primates and humans. The present initiative focuses on the synthesis of current GMP (Good Manufacturing Practices) and non-GMP compounds for basic and clinical research such as novel central nervous system receptor subtype-selective agonists and antagonists, radiolabeled compounds, and novel PET, SPECT, and fMRI ligands for functional brain imaging.

## Key facts

- **NIH application ID:** 11200931
- **Project number:** 75N95022D00016-0-759502400002-1
- **Recipient organization:** RESEARCH TRIANGLE INSTITUTE
- **Principal Investigator:** WAYNE MASCARELLA
- **Activity code:** N01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $376,358
- **Award type:** —
- **Project period:** 2024-06-16 → 2025-06-15

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11200931

## Citation

> US National Institutes of Health, RePORTER application 11200931, NIMH SYNTHESIS AND DISTRIBUTION OF DRUGS OF ABUSE AND RELATED COMPOUNDS. JUNE 16, 2024 - JUNE 15, 2025. TASK ORDER 75N95024F00002 (TO7). N01DA-22-8944. (75N95022D00016-0-759502400002-1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/11200931. Licensed CC0.

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