Triton will develop a low-cost, at-home, paper-based vertical flow assay PSA detection test kit with prostate cancer biopsy risk calculation algorithm based on our previously developed technologies with a classifier for prostate cancer risk integrating the personal risk factors using a finger stick to obtain a blood sample at the price less than $20.00. Successful development of a low cost, simple-to-use, home-based test kit for PSA screening for prostate cancer with a classification algorithm will enable patients to decide whether to seek medical help or keep monitoring, will be reducing cancer mortality especially for high risked population.