Project Summary Capstone Senior Design courses enable bioengineering (BIOE) seniors to engage with the design process and apply technical fundamentals and industry related topics, ultimately generating a functional prototype. Our capstone program at Rice University, solicits project ideas from research faculty, physicians, and industry leaders. Interdisciplinary teams drive the prototype development throughout the year and submit oral presentation and documentation deliverables. Students in our capstone program enjoy immense advantage oered by a well-equipped design facility and infrastructure at Rice University to support projects from the Texas Medical Center, home to the world’s largest children’s and cancer hospital and the largest medical city in the world. These strengths, along with the cross-disciplinary teams (mechanical engineering, electrical engineering and global health technologies) rigorous senior design documentation, and oral deliverables, lead to teams placing nationally in competitions each year. Eective capstone program design, however, demands an engaged clinical experience, an area lacking in many existing programs, including ours. To address this, we propose the creation of a novel clinical immersion program with a focus on human centered design and disparities in healthcare delivery. Our program will consist of a cohort of five bioengineering seniors selected through an application process. The cohort will attend didactic lectures on topics such as design process, needs finding, disparities in healthcare delivery, universal design, storyboarding, stakeholder communication and design de-risking. Students will apply their learnings by immersive engagement in two clinical environments: 1) Pediatric Intensive Care Unit in Texas Children’s Hospital and 2) Texas Heart Institute. Exercises such as iterative storyboarding, daily individual and group reflections and case study research on the evolution of a device design will elucidate areas of cl