To meet the healthcare challenges on which the NEI focuses, it is essential that we nurture and build the physician-scientist workforce, preparing medical students from all areas of the US to become tomorrow’s researchers. Over the past three decades the University of Utah School of Medicine (UUSOM), which includes the Department of Ophthalmology and Visual Sciences and the Moran Eye Center, has built a dynamic research community that addresses the full range of eye-related health issues. Faculty members’ grant-funded research spans the continuum of T1-T4 translational science and is supported by numerous institutional programs. A large number of our medical students are interested in eye health, as evidenced by 29% regularly participating in monthly meetings of the medical student-run Ophthalmology Interest Group. In addition, faculty members have extensive experience in successfully mentoring trainees, helping to build the physician-scientist, and scientifically minded physician, workforce. Thus, the UUSOM is an ideal location to offer outstanding short- term research experiences for medical students. The goal and objectives of the Medical Student Research Program in Eye Health and Disease (MSRP-EHD) are to: GOAL: Ignite in medical students a life-long interest in conducting or collaborating in the translational field of vision research, while also building their skills in creative and critical thinking. Objective 1: Expose 5 medical students/year to EHD-associated research opportunities spanning the translational research spectrum (T0 to T4). Trainees will participate in a mentored, 10-week summer research experience between their first and second years of medical school and develop creative and critical thinking skills through an innovative summer course. Objective 2: Engage in the exciting foundational, clinical. and translational science discoveries taking place at the University of Utah. Sixteen faculty mentors have agreed to participate in the program. The P