PROJECT SUMMARY (Injury Control Research to Practice and Policy Core) Injury poses the greatest threat to life for those under 40 years of age and is a prevalent cause of morbidity and mortality across the lifespan. Rigorous research is needed to address the spectrum of injury prevention across the lifespan given the enormous burden trauma and injury pose to both individual and public health. Strategies are needed to prevent injuries (e.g., older adults with falls), and identify those at risk of recurrent injury or morbidity (e.g., non-accidental childhood trauma). This must also be coupled with efforts to mitigate the consequences of adverse post-traumatic sequelae (e.g., post-traumatic stress disorder). Beyond the conduct of high quality, efficient research, it is imperative to design injury control research such that it can rapidly be integrated into public health policies and clinical practice (‘Research to Policy and Practice’). In typical research practice, it takes years to conduct research and disseminate research findings to target audiences; by the time research findings are available these strategies can be often outdated. It is necessary to conceptualize future translation, dissemination and implementation from the moment of research conceptualization and throughout the research process. The Injury Control Research to Practice and Policy (RPP) Core will equip COBRE affiliated investigators with tools to tailor their study methodologies and dissemination strategies for accelerated impact on in clinical practice and policy. The objective of the RPP Core is to establish a regional and national hub leading the development, conduct, analysis and dissemination of high-quality, scientifically sound injury control research. The RPP Core will feature rigorous support to design, implement, and disseminate studies capable of practice or policy level change. This objective will be reached through the following specific aims: 1) provide a robust infrastructure of met