# Wisconsin Alzheimer's Disease Research Center

> **NIH AG P30** · UNIVERSITY OF WISCONSIN-MADISON · 2026 · $4,413,740

## Abstract

The overarching goal of the renewal of the Wisconsin Alzheimer’s Disease Research Center (ADRC) is to conduct breakthrough research on the pathobiology, preclinical biomarkers, early diagnosis, treatment, and prevention of Alzheimer’s disease (AD) and related dementias. This goal will be accomplished by establishing a stimulating, interdisciplinary environment for collaborative, equitable, and generalizable research that provides invaluable clinical data, ante-mortem biospecimens, and autopsy brain tissue. Funded by NIA in 2009, the Wisconsin ADRC will oversee eight well-integrated Cores and the Research Education Component that will support timely, innovative research, which will: 1) characterize preclinical biomarkers of AD and their role in predicting transition from preclinical to clinical stages of the disease; 2) investigate the neurobiology of AD; 3) identify novel vascular and genetic risk factors, linking them to the disease pathology and clinical phenotype; 4) incorporate contemporary biochemical and molecular techniques into clinical-pathologic cohort studies, including multidimensional omics and next generation sequencing; and 5) participate and facilitate the missions of other federal, state, and local agency-supported aging and dementia research programs. The overall goals of the Center will be accomplished through coordinated activities of its eight Cores and the REC. The Administrative Core will provide scientific leadership to the ADRC. The Clinical Core will perform standardized evaluations and collect UDS and additional data on all research participants. It will work closely with the Outreach, Recruitment and Engagement (ORE) and the Community Partnership (CP) Cores to enhance enrollment of participants from underrepresented groups. The Data Management and Statistical (DMS) Core will continue to meet all data management, informatics, and statistical needs and support all the PC- and web-based services and processes. The Neuropathology Core will co

## Key facts

- **NIH application ID:** 11381763
- **Project number:** 5P30AG062715-08
- **Recipient organization:** UNIVERSITY OF WISCONSIN-MADISON
- **Principal Investigator:** Sanjay  Asthana
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** AG
- **Fiscal year:** 2026
- **Award amount:** $4,413,740
- **Award type:** 5
- **Project period:** 2019-05-01T00:00:00 → 2029-03-31T00:00:00

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11381763

## Citation

> US National Institutes of Health, RePORTER application 11381763, Wisconsin Alzheimer's Disease Research Center (5P30AG062715-08). Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/grant/nih/11381763. Licensed CC0.

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