“Opioid overdose death (OOD) rates among Black Americans have increased unabated since 2015, outpacing national averages at a rate of two to one. Health disparities in the growth rate of OOD have been documented in at least 23 states, including Missouri, which has second highest rate of OOD among Black Americans: 44 per 100,000 (relative to 16 per 100,000 nationally). There is a critical need to identify and mitigate environmental determinants of health (EDOH) that drive increasing health disparities in OOD and opioid use disorder treatment utilization. One strategy that addresses EDOH—such as low geographic access to treatment and high neighborhood deprivation—is community-based outreach, which dispatches peers and community health workers to provide overdose education, naloxone distribution, and linkage to evidence-based treatment. Although these efforts can improve psychoeducation and access to treatment for Black Americans, existing outreach interventions are limited by a lack of data-driven targets. There is an urgent need to identify and disseminate geographic and environmental drivers of OOD among Black Americans to improve the efficacy of existing outreach interventions and in turn, develop data-driven solutions to health disparities affecting this population. The current K08 addresses this need by integrating geospatial information systems (GIS) technology and community based participatory research to create a digital tool designed to 1) identify current EDOH that underlie OOD among Black Americans and 2) provide data-driven targets to improve the efficacy of community-based outreach interventions. The project aims and career development plan will concurrently support Dr. Banks’ transition to an independent clinical investigator focused on the integration of technology and community engagement to improve substance use treatment among populations facing health disparities. Specific aims of the project are to: 1) develop and evaluate the predictive validity o