# Core B - Statistical and Data Management

> **NIH NIH P01** · ST. JOSEPH'S HOSPITAL AND MEDICAL CENTER · 2020 · $170,218

## Abstract

Core B: Abstract
The overall goal of the Statistics and Data Management Core (Core B) is to continue providing
the computational and analytic resources to support the overall Program Project Grant (PPG)
mission of elucidating the molecular neurobiology of mild cognitive impairment (MCI). More
specifically, Core B will assist with study design, tissue selection, data management, statistical
analysis, and results interpretation to ensure the success of each PPG investigator. Specifically,
the core will provide data management linking existing clinical and neuropathological data from
the Rush Religious Orders Study (RROS) housed in the Rush Alzheimer’s Disease Core Center
(RADCC) with the cellular and molecular findings from the three proposed Program Project Grant
(PPG) components. To accomplish this, Core B will: Extract and retrieve relevant data from the
RROS clinical and neuropathological databases; expand, document, and maintain a
PPG data library and merge RROS data with data generated by the PPG research projects for
statistical analysis. In addition, Core B will identify eligible cases based upon inclusion/exclusion
criteria specified by the PPG while maintaining blinding to clinical and pathological diagnoses.
Finally, provide statistical support for study design, prepare all analytic data sets across projects,
perform statistical analyses as needed, and assure statistical accuracy in interpretation and
presentation of results. The statistical research team is experienced in the conduct of
neuropathological studies involving human tissue samples.

## Key facts

- **NIH application ID:** 9703470
- **Project number:** 2P01AG014449-22
- **Recipient organization:** ST. JOSEPH'S HOSPITAL AND MEDICAL CENTER
- **Principal Investigator:** Michael Malek-Ahmadi
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $170,218
- **Award type:** 2
- **Project period:** — → 2025-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9703470

## Citation

> US National Institutes of Health, RePORTER application 9703470, Core B - Statistical and Data Management (2P01AG014449-22). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9703470. Licensed CC0.

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