# Administrative Core: Systems Biology to Identify Biomarkers of Neonatal Vaccine Immunogenicity

> **NIH NIH U19** · BOSTON CHILDREN'S HOSPITAL · 2020 · $111,164

## Abstract

Project Summary
Our overall HIPC proposal, entitled “Systems Biology to Identify Biomarkers of Neonatal Vaccine
Immunogenicity”, will leverage cutting-edge Projects and Cores to identify age-specific OMIC signatures
that correlate with vaccine immunogenicity in newborns and infants recruited at Clinical Core (CC)-Sites
in West Africa (The Gambia) and Australasia (Papua New Guinea). Given the scientific scope, complexity,
and geographic range of the proposed work, a well-designed Administrative Core will be crucial to
optimize the quality and impact of the proposed studies and to ensure provision of project deliverables.
The goal of our Administrative Core is to institute streamlined processes facilitating seamless, synergistic,
and productive interactions among investigators from each HIPC Project and Core. We will achieve this
goal by pursuing the following Specific Aims (SAs):
SA1. Provide infrastructure for administrative leadership aimed at building an interactive and
collaborative working team resulting in maximal project synergy
SA2. Facilitate and promote communication and interactions amongst the Project and Core Leads by
conducting regular teleconferences/face-to-face meetings, annual meetings, as well as seminars/symposia
focused on the HIPC.
SA3. Manage and optimize communication within the HIPC and between the HIPC and HIPC Steering
Committee.
SA4. Resolve potential conflicts that might arise within and outside of our HIPC by implementing
recommendations of the Conflicts Resolution Group (CRG).
SA5. Provide fiscal, regulatory and scientific oversight, review and consolidate yearly progress reports
sent to the NIH.
SA6. Protect intellectual property rights of our investigators and execute material transfer agreements.
SA7. Implement the data management/sharing plan among investigators within and outside of our HIPC
team.
Overall, the HIPC Administrative Core will ensure appropriate stewardship of NIH funds,
adherence to HIPC project timelines, and will optimize and amplify the scientific impact of the
proposed studies.

## Key facts

- **NIH application ID:** 9822168
- **Project number:** 5U19AI118608-04
- **Recipient organization:** BOSTON CHILDREN'S HOSPITAL
- **Principal Investigator:** OFER LEVY
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $111,164
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9822168

## Citation

> US National Institutes of Health, RePORTER application 9822168, Administrative Core: Systems Biology to Identify Biomarkers of Neonatal Vaccine Immunogenicity (5U19AI118608-04). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9822168. Licensed CC0.

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