# Bioinformatics

> **NIH NIH P30** · UNIV OF NORTH CAROLINA CHAPEL HILL · 2020 · $477,782

## Abstract

ABSTRACT Bioinformatics (BIONFF) Shared Resource 
The Lineberger Bioinformatics Shared Resource (BIONFF) is a multifaceted shared resource established to 
serve the ever growing computational, data and analytic needs of the LCCC. Our expertise in bioinformatics 
began with the genomics program, particularly gene expression microarray analysis. The growing need for 
analysis, large data set management and storage, and integration with clinical and population characteristics 
necessitated a Lineberger-wide approach. This resulted in the creation of the UNC Lineberger Bioinformatics 
Shared Resource and its successful review five years ago. The continued explosion of genomics, proteomic 
and other clinical and population data in cancer research spurred an ever greater emphasis on integration of 
laboratory and clinical systems to facilitate high impact translational research. Fulfillment of this need required 
a growing UNC Lineberger investment in computational infrastructure, software, personnel, and systems 
developments. BIONF leveraged this investment toward a common infrastructure that now supports many 
other Lineberger Shared Resources, research programs, and individual labs. This development included a 
common computational infrastructure (i.e. Lineberger Data Warehouse) to integrate multiple distinct data 
sources, scalable software and system development, and increased analytic capacity. As data storage and 
analytical needs grow, the BIONF has identified specific areas of growth and development for the next 5 years 
for the LCCC members to continue to perform as a national and international leader in basic biology, 
computational genomics, translational, population and clinical research. Substantial high impact research 
highlights resulted from this shared resource. The most easily identified were the multi-level analysis for TCGA 
publications but this Shared Resource touched virtually every Center program and research effort with data 
intensive needs.

## Key facts

- **NIH application ID:** 9834855
- **Project number:** 5P30CA016086-44
- **Recipient organization:** UNIV OF NORTH CAROLINA CHAPEL HILL
- **Principal Investigator:** CHARLES M PEROU
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $477,782
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9834855

## Citation

> US National Institutes of Health, RePORTER application 9834855, Bioinformatics (5P30CA016086-44). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9834855. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*