# Biostatistics

> **NIH NIH P30** · UNIV OF NORTH CAROLINA CHAPEL HILL · 2020 · $397,975

## Abstract

ASTRACT - Biostatistics (BIOS) Shared Resource 
The principal objective of the Biostatistics (BIOS) SR Facility is to provide the highest level possible of quality 
statistical consultation services to UNC’s Lineberger Comprehensive Cancer Center (LCCC) members. BIOS 
provides Cancer Center members support for the design, conduct, analysis, and generation of manuscripts for 
their research. BIOS adds value to the LCCC through close collaboration with multiple center members 
providing invaluable expertise for their research. Areas of expertise in support of future use by LCCC members 
include clinical trials and other forms of clinical research, computational biology, genomics, genetics, cancer 
epidemiology, quality of life, outcomes, and other forms of population sciences research. BIOS also provides 
service and leadership on complex and multi-component applications such as SPORE and Program Project 
grants and investigator initiated trials. BIOS SR’s service and leadership on the Protocol Review, Data and 
Safety Monitoring Committees greatly benefits LCCC member research efforts. 
Highlights of statistical science that directly benefits LCCC member-related research include: a novel approach 
to unsupervised screening of genetic loci across RNA-seq cohorts, sampling helps understand organizational 
correlates of adolescent immunization, clinical trialists benefit from advances in statistical approaches in 
oncology drug development and efficient designs for phase II oncology trials with ordinal outcome, and 
statistical methods for high-throughput sequencing technology in DAE-seq (DNA after enrichment sequencing) 
data analysis improves results. 
In 2014, 10,775 hours of consultative and other biostatical services were utilized. Since 2010, the BIOS user 
group grew and diversified, particularly those members needing assistance with statistical methods for basic 
science/genomic, clinical/translational, and population sciences research. Requested CCSG funding is 
$288,650, representing 30% of projected operating costs. The BIOS SR plans to expand statistical areas of 
expertise to meet the expected and growing needs of Cancer Center members.

## Key facts

- **NIH application ID:** 9834856
- **Project number:** 5P30CA016086-44
- **Recipient organization:** UNIV OF NORTH CAROLINA CHAPEL HILL
- **Principal Investigator:** JOSEPH G IBRAHIM
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $397,975
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9834856

## Citation

> US National Institutes of Health, RePORTER application 9834856, Biostatistics (5P30CA016086-44). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9834856. Licensed CC0.

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