# Translational Pathology

> **NIH NIH P30** · UNIV OF NORTH CAROLINA CHAPEL HILL · 2020 · $299,148

## Abstract

ABSTRACT-Translational Pathology (TP) Shared Resource 
The Translational Pathology (TP) is a valuable resource for all aspects of experimental pathology for Cancer 
Center members conducting basic, translational, and clinical cancer research. The TP combines two 
successful LCCC cores under joint management, the Animal Histopathology Core, serving pre-clinical 
researchers utilizing animal models, and the Translational Pathology Laboratory, serving clinical researchers 
utilizing archival patient tissues from the TPF and UNC Hospitals. The TP adds value to the Cancer Center by 
offering its investigators competitive pricing on a wide range of histopathology services at an on -campus 
location with convenient access to expert pathology consultation. The Core is co-directed by Faculty Directors 
Ryan Miller, MD, PhD, and Stephanie Montgomery, DVM, PhD, who together have expertise in human and 
animal diseases, along with the guidance and experience of Facility Directors Nana Nikolaishvili Feinberg, 
PhD, and Dawud Hilliard. Dr. Bernand Weismann has been leading the Animal Histopathology component on 
an interim basis since Dr. Roger’s departure. The Core staff provides a wide range of histology services, 
including tissue embedding and sectioning (frozen and paraffin), routine and special histologic stains, 
consultation on study design and tissue collection, tissue microarray (TMA) design and construction, single and 
multiplex immunohistochemistry, RNA in situ hybridization (ISH), and advanced digital pathology services. 
During the last grant cycle, the Core has grown with added services and personnel, driven by increased NIH 
funding awarded to UNC investigators, expanded on-campus animal housing facilities, and the maturation of 
large on-campus initiatives, including the Collaborative Cross and Mouse Phase 1 Unit. During the next 
funding period, the TP will expand available services and technologies to meet the demands of Cancer Center 
investigators, including advancing available animal immunohistochemistry and immunofluorescence reagents, 
developing FISH assay using commercially available PNA (peptide nucleic acid) and LSI/CEP probes, and 
acquiring a new state-of –the-art fluorescent scanner with higher speed, capacity, and magnification for 
scanning of IF and FISH slides. Accordingly, we request an increased budget of $216,836 representing 5% of 
the total TP budget to promote expanded utilization and capabilities.

## Key facts

- **NIH application ID:** 9834862
- **Project number:** 5P30CA016086-44
- **Recipient organization:** UNIV OF NORTH CAROLINA CHAPEL HILL
- **Principal Investigator:** Christopher Ryan Miller
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $299,148
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9834862

## Citation

> US National Institutes of Health, RePORTER application 9834862, Translational Pathology (5P30CA016086-44). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9834862. Licensed CC0.

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