# PROTOCOL REVIEW AND MONITORING SYSTEM (Core 019)

> **NIH NIH P30** · UNIV OF NORTH CAROLINA CHAPEL HILL · 2020 · $143,396

## Abstract

Abstract – Protocol Review and Monitoring System (PRMS) 
The UNC Lineberger Comprehensive Cancer Center's PRMS facilitates internal oversight of the scientific 
aspects of all cancer clinical trials at the University of North Carolina focusing on the scientific merit, priorities, 
and progress of clinical protocol research. The system is a multi-step process with preliminary review by 
Protocol Office Disease teams (PODs) and the Protocol Office Executive Committee (POEC), followed by a 
formal review by the Protocol Review Committee (PRC). 
The PRC is chaired by Peter Voorhees, MD, and meets bi-monthly to review every cancer-related clinical 
protocol before it is submitted to The Office of Human Research Ethics' Institutional Review Board (IRB). The 
PRC's primary function is to ensure the scientific quality of proposed studies. As described in Clinical Protocol 
and Data Management (CPDM), PODs and POEC review protocols for feasibility, quality, and priority before 
they are submitted to the PRC. The PRC monitors study accrual and has the authority to close under- 
performing trials. During 2014, the PRC reviewed 295 protocols -- 112 new studies and 183 active trials for 
renewal and monitoring.

## Key facts

- **NIH application ID:** 9834868
- **Project number:** 5P30CA016086-44
- **Recipient organization:** UNIV OF NORTH CAROLINA CHAPEL HILL
- **Principal Investigator:** PETER VOORHEES
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $143,396
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9834868

## Citation

> US National Institutes of Health, RePORTER application 9834868, PROTOCOL REVIEW AND MONITORING SYSTEM (Core 019) (5P30CA016086-44). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9834868. Licensed CC0.

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