# Shared Resource: Biobanking and Correlative Sciences

> **NIH NIH P30** · WAYNE STATE UNIVERSITY · 2020 · $120,502

## Abstract

PROJECT SUMMARY/ ABSTRACT 
The purpose of the Biobanking and Correlative Sciences (BCS) Core is to enhance the peer reviewed, 
funded research activities of KCI members whose research requires IRB-approved access to patient tissue for 
preclinical and clinical studies and to support clinical trials by managing tissue specimens and providing 
circulating tumor cell counting. The BCS Core is grouped in the Cross Disciplinary Research Core Cluster 
which, in addition to the BCS Core, includes the Biostatistics, Genomics, and Pharmacology Cores. 
The BCS Core provides KCI investigators with high quality, well-annotated tumor tissue specimens for pre- 
clinical studies and coordinates requests for tumor tissues with the Genomics, Pharmacology and 
Proteomics Cores. Disease site-specific pathologists review tissues for selection of appropriate samples. 
This ensures there is appropriate and adequate tissue in the amounts and numbers needed for a given study 
to provide biologically meaningful results as determined by the Biostatistics Core. Institutional funds support 
the contributions of the pathologists. 
Fresh frozen specimens in the KCI Biobank are stored in eight -80⁰C freezers, which are temperature 
monitored and have back up emergency power. All specimens are barcoded and stored in cryosafe 
containers. Secured cabinets store formalin-fixed paraffin embedded (FFPE) specimens and any prepared 
slides from the biospecimens. Each biospecimen is logged into the KCI database, OnCore®, with its precise 
location, associated informed consent, pathology report, and amount of available tissue. Histology services 
are supported by a tissue processor, a tissue embedder, microtomes, a cryostat, and other ancillary histology 
equipment. For pharmacodynamic assays, the core contains a Janssen Cell Search Circulating Tumor Cell 
system, which enables investigators to enumerate and/or isolate circulating tumor cells. 
The services provided by the Biobanking and Correlative Sciences Core have contributed to 21 peer- 
reviewed publications during the current review period.

## Key facts

- **NIH application ID:** 9836635
- **Project number:** 5P30CA022453-38
- **Recipient organization:** WAYNE STATE UNIVERSITY
- **Principal Investigator:** Julie Lynn Boerner
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $120,502
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9836635

## Citation

> US National Institutes of Health, RePORTER application 9836635, Shared Resource: Biobanking and Correlative Sciences (5P30CA022453-38). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/9836635. Licensed CC0.

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