# Shared Resource: Biostatistics

> **NIH NIH P30** · WAYNE STATE UNIVERSITY · 2020 · $488,991

## Abstract

ABSTRACT 
The Biostatistics Core provides expertise in statistical science to ensure scientific rigor in study design, 
statistical analysis, and interpretation of cancer research studies. The Biostatistics Core is grouped in the 
Cross Disciplinary Research Core Cluster which, in addition to the Biostatistics Core, includes the 
Pharmacology, Genomics, and Biobanking and Correlative Sciences Cores. 
Members of the Core have expertise in a wide range of scientific disciplines including design and analysis of 
clinical trials, observational studies, in vitro and in vivo studies, biomarker discovery and validation projects, 
bioinformatics projects in collaboration with the Genomics Core and metabolomics studies in collaboration 
with the Pharmacology Core. They collaborate with cancer center investigators in the planning phase of 
studies to ensure that their hypotheses are testable and that the data will be adequate to address the study 
questions. They provide expertise on data collection and management and devise analysis plans consistent 
with the study objectives. At the completion of the study they evaluate the data for conformity with the 
assumptions of the statistical tests, provide estimates of the endpoints with confidence intervals, develop 
appropriate statistical models, assess the adequacy of the models and prepare written reports to the 
investigator. The Biostatistics Core has an important role in cancer research at KCI. During the current grant 
period (12/1/2010 -- 11/30/2014), the Core's collaborative activities resulted in 121 clinical protocols and 263 
new cancer research proposals submitted for peer reviewed, external funding. Of these, 178 were submitted 
to the NCI, 36 to the DOD, and 4 to the Susan G. Komen Foundation. In addition, Biostatistics Core 
members were co-authors on 87 publications in peer reviewed journals. Core biostatisticians collaborate with 
investigators from each of the KCI research programs and work with staff from other KCI cores. 
The Core maintains a variety of statistical applications including general-purpose statistical software, R, SAS 
and Stata/MP, as well as software for statistical power calculations including PASS and nQuery Advisor. The 
Core shares an Ingenuity Pathway Analysis (IPA) license with the Genomics Core. Application software 
resides on a high-performance, multi-processor Dell 820 server. Access to the server is restricted to members 
of the Biostatistics Core and authorized guests. For intensive computing projects, members of the Core use 
the WSU high-performance grid, four servers of which have been contributed to KCI, running under Linux, for 
the use of Core members. These computers are accessible to other authorized KCI members whose research 
requires high performance computing.

## Key facts

- **NIH application ID:** 9836636
- **Project number:** 5P30CA022453-38
- **Recipient organization:** WAYNE STATE UNIVERSITY
- **Principal Investigator:** Judith Abrams
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $488,991
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9836636

## Citation

> US National Institutes of Health, RePORTER application 9836636, Shared Resource: Biostatistics (5P30CA022453-38). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/9836636. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*