# Clinical Protocol and Data Management (Core 012)

> **NIH NIH P30** · UNIVERSITY OF PENNSYLVANIA · 2020 · $965,073

## Abstract

Project Summary 
Clinical Protocol and Data Management (CPDM) is the administrative home for all of the units that support 
clinical research at the Abramson Cancer Center (ACC), providing essential support for and monitoring of all 
clinical research conducted in the ACC regardless of the type of intervention or sponsor. The CPDM, in 
collaboration with ACC Leadership, creates, directs and enforces the operational standards (policies) and 
expectations for the conduct of all clinical research within the ACC. The CPDM scope is of necessity broad, 
encompassing development and updating of policies and procedures, education and training, supervision of 
data managers and research nurses, and oversight over all of the specialty clinical research units within our 
Center. The CPDM manages our centralized Clinical Trials Management System (CTMS), Velos, organizes 
and performs quality assurance and QC/monitoring of clinical trials across the center, and directly manages the 
complex, ongoing and recurring activities of our mandatory clinical research review committees. Key units 
supported by the CPDM are the Department of Compliance and Monitoring (DOCM), the Protocol Review and 
Monitoring System (PRMS, known as the Clinical Trials Scientific Review and Monitoring Committee 
[CTSRMC]), the Data and Safety Monitoring Committee (DSMC), and the Clinical Research Unit (CRU). 
While CPDM provides the administrative support for PRMS and DSMC, it is vital to note that these are, by 
design, distinct entities. PRMS is described elsewhere in this renewal. The inclusion of Women and 
Minorities in clinical trials is a central focus of ACC Leadership and clinical investigators as a component of 
our commitment to addressing the cancer burden in minority and underserved populations. During the current 
award period, the ACC implemented several initiatives aimed at reducing disparities in cancer incidence and 
mortality in minorities, including completion of quality improvement training to further increase the diversity of 
the patients on cancer clinical trials at ACC, establishment of additional key partnerships with community 
organizations to increase educational efforts and community outreach, creation of cancer screening navigation 
programs that increase patient engagement and improve access to and completion of cancer screening tests, 
and recruitment of a cadre of patient navigators for common diseases in our catchment area affecting 
minorities, including lung, colorectal and breast cancer, in order to assist patients from all backgrounds in 
getting into our health care system and using it effectively. Children with cancer have traditionally had a very 
high participation rate in clinical research studies with the field of pediatric oncology often at the forefront of 
cancer clinical research. The ACC Pediatric Oncology Program has played a central role locally and nationally 
in improving our understanding of the biology of childhood cancers through ...

## Key facts

- **NIH application ID:** 9836823
- **Project number:** 5P30CA016520-44
- **Recipient organization:** UNIVERSITY OF PENNSYLVANIA
- **Principal Investigator:** DAN TOBY VOGL
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $965,073
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9836823

## Citation

> US National Institutes of Health, RePORTER application 9836823, Clinical Protocol and Data Management (Core 012) (5P30CA016520-44). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9836823. Licensed CC0.

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