# Community Surveillance of Coronary Heart Disease

> **NIH NIH R01** · UNIV OF MASSACHUSETTS MED SCH WORCESTER · 2020 · $768,763

## Abstract

Project Summary/Abstract
 Preventing the onset of acute myocardial infarction (AMI) and its recurrence, and reducing the morbidity
and mortality associated with AMI, remain of significant public health and clinical concern. Monitoring
contemporary trends in AMI incidence, treatment, and in-hospital and long-term outcomes is of considerable
importance given periodic national updates of treatment guidelines, emphasis on reducing hospital
readmissions, and revised definitions and classifications of AMI. Continuously supported by the NHLBI, we
have conducted more than 35 years of population-based surveillance of AMI incidence and attack rates,
hospital management practices, and the in-hospital and long-term prognosis associated with AMI among
residents of central MA hospitalized at all central MA medical centers. We have a highly experienced team of
cardiologists, epidemiologists, clinical informatics, and health services researchers who will build on multi-
decade long trends (1975-2011) in our principal study endpoints examined previously in this study to the two
new study years of patients hospitalized with AMI at all central MA medical centers in 2014 and 2017.
 To sustain our efforts into the era of electronic medical records (EMRs), and after implementation of the
ICD-10 system in 2015, we will develop a new automated AMI surveillance system that efficiently utilizes
EMRs by taking advantage of state-of-art natural language processing (NLP) methods that will be compatible
with ICD-10 (Aim 1). We will use the new NLP method to streamline traditional chart review-based collection of
socio-demographic, clinical, treatment, and hospital and post-discharge outcomes data in patients hospitalized
with AMI at all 11 central MA medical centers in 2014 and 2017. The data extracted from NLP-streamlined
chart reviews will be used to validate and refine the NLP system. Issues related to changes from ICD-9 to ICD-
10 will be carefully addressed. The new NLP-enriched EMR-based surveillance system will eventually be
implemented in all participating central MA hospitals. Using the NLP-enriched and EMR-based surveillance
data, we will monitor the contemporary clinical epidemiology of AMI, and out-of-hospital deaths due to coronary
disease, and changing landscape, over a more than 40 year period (1975-2017) (Aim 2).
 The new EMR-based and NLP-enriched system will enhance the population-based surveillance of acute
coronary disease. This new system will be cost-effective, more efficient and near-real time, have greater
accuracy and precision, and can be readily updated to accommodate changes in information technologies and
broadly applicable to other hospital systems. It will support our continued efforts to provide unique community-
based observational data on several populations that are often excluded from clinical trials, and that are
increasing in numbers, namely the elderly and patients with multiple morbidities. Furthermore, it will generate
critical data to...

## Key facts

- **NIH application ID:** 9838247
- **Project number:** 5R01HL135219-04
- **Recipient organization:** UNIV OF MASSACHUSETTS MED SCH WORCESTER
- **Principal Investigator:** ROBERT JOEL GOLDBERG
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $768,763
- **Award type:** 5
- **Project period:** 2016-12-15 → 2021-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9838247

## Citation

> US National Institutes of Health, RePORTER application 9838247, Community Surveillance of Coronary Heart Disease (5R01HL135219-04). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9838247. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*
