# Cardiometabolic Outcomes in Multi-ethnic Physical Activity & Sedentary Behavior Study (COMPASS)

> **NIH NIH R01** · ALBERT EINSTEIN COLLEGE OF MEDICINE · 2020 · $743,025

## Abstract

US Hispanics/Latinos are the largest US minority group, constituting over 15% of the US
population and growing to one-third of the US population by 2050. Hispanics match or exceed
any other race-ethnicity group in having a high burden of diabetes and pre-diabetes. Especially
given the relatively young age of US Hispanics, the group with prediabetes (e.g.,fasting plasma
glucose 100-125 mg/dl) are of immense public health importance because 15-30% of people
with prediabetes will develop diabetes within five years.
Physical activity (PA) is an effective preventive behavior in the battle to prevent diabetes as
suggested by the Diabetes Prevention Program. In this context, the Hispanic population
presents a paradox. Particularly among males, Hispanics have higher moderate-to-vigorous
activity levels than non-Hispanics and light intensity PA is higher and sedentary behavior (SB) is
lower among Hispanics than other groups. There is also an apparent contradiction (Hispanic
paradox) between a high risk of prediabetes/diabetes among Hispanics, while at the same time
Hispanics have favorable mortality rates vs. others and may also have lower incidence of
cardiovascular disease (CVD).
The present application will leverage the Hispanic Community Health Study/Study of Latino
Hispanics as well as the Framingham Heart Study (FHS) Third Generation and Omni Gen 2
(FHS Gen3/Omni2) cohorts of multiple race/ethnic groups. This approach not only increases
generalizability of our findings to the US mainstream population, but also helps us understand
what is unique about Hispanics. In all, 5500 individuals with confirmed prediabetes will be
studied, all of whom had 7-day baseline Actical accelerometry measurements (2008-2011)
which will be repeated during 2017-2020. This approach will allow us to understand the
relationship among PA, SB, onset of diabetes and CVD in a large, representative population
study of prediabetics.

## Key facts

- **NIH application ID:** 9838784
- **Project number:** 5R01HL136266-05
- **Recipient organization:** ALBERT EINSTEIN COLLEGE OF MEDICINE
- **Principal Investigator:** Robert C Kaplan
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $743,025
- **Award type:** 5
- **Project period:** 2016-12-15 → 2023-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9838784

## Citation

> US National Institutes of Health, RePORTER application 9838784, Cardiometabolic Outcomes in Multi-ethnic Physical Activity & Sedentary Behavior Study (COMPASS) (5R01HL136266-05). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9838784. Licensed CC0.

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