# Physiology Core

> **NIH NIH P01** · MEDICAL COLLEGE OF WISCONSIN · 2020 · $344,960

## Abstract

CORE C PROJECT SUMMARY
The Core C (Physiology Core) for the MCW program project grant, entitled “Renal Mechanisms in Blood Pressure
Control”, will support program project investigators with comprehensive biochemical, microscopy,
electrophysiological, and phenotyping services to assess physiological and pathophysiological function of the
kidney in the control of blood pressure. The need for Core C is apparent considering the current heavy use and
anticipated use in the proposed protocols. Throughout the history of the PPG, Core C has provided centralized,
standardized research services that have enabled program investigators to engage in cutting edge research.
The overall goal of Core C is to assist program project investigators with the application of many of the basic and
more-comprehensive analyses relevant to the study of kidney physiology and its relationship to the blood
pressure control at the cellular, organ, and whole animal level. Multiple approaches will be offered, including
biochemical analysis, chronic blood pressure measurement by telemetry or indwelling catheters, laser-Doppler
flowmetry, GFR measurement, biosensors, fluorescence probes, and electrophysiology analysis in freshly
isolated tubules. Core C will serve as an invaluable resource for the project investigators to define the specific
mechanisms that lead to the control of blood pressure and kidney diseases. Core staff will also assist in
experimental design and training of the laboratory staff, and participate in data collection and analysis.

## Key facts

- **NIH application ID:** 9841972
- **Project number:** 5P01HL116264-08
- **Recipient organization:** MEDICAL COLLEGE OF WISCONSIN
- **Principal Investigator:** Alexander Staruschenko
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $344,960
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9841972

## Citation

> US National Institutes of Health, RePORTER application 9841972, Physiology Core (5P01HL116264-08). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9841972. Licensed CC0.

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