# Program 34: Lung Cancer

> **NIH NIH P30** · DANA-FARBER CANCER INST · 2020 · $70,961

## Abstract

Lung Cancer Program
Project Summary / Abstract
The Lung Cancer Program seeks to exploit the resources provided by the consortium of DF/HCC institutions to
conduct innovative population-based research on the causes and pathogenesis of lung cancer, focusing on
discoveries that will ultimately lead to improvements in prevention, diagnosis, prognosis, and therapy. The
Program has focused on making discoveries about the pathogenesis of lung cancer and using these
discoveries to apply novel, effective therapies to both prevent and treat the different types of lung cancer. The
program has four specific aims: 1) Identify germline polymorphisms and determine their role in the
susceptibility, pathogenesis and prognosis of lung cancer; 2) Define pathogenic mechanisms underlying the
development of lung cancer; 3) Exploit the discoveries in pathogenesis to develop novel therapeutic
approaches to thoracic malignancies; and 4) Characterize the mechanisms of acquired resistance to
targeted therapy and immunotherapy and develop methods to overcome the resistance. The program has
63 members, representing six DF/HCC institutions and 11 academic departments. In 2014 peer-reviewed grant
funding attributed to the Program was $6.1 million in total costs from the NCI and $1.8 million from other
sponsors. During the current funding period, Lung Cancer Program members published 1,214 cancer-relevant
papers. Of these 32% were inter-institutional, 27% were intra-programmatic, and 51% were inter-programmatic
collaborations between two or more DF/HCC members. Overall, when counted once, 27% of DF/HCC
publications were inter-programmatic collaborations.

## Key facts

- **NIH application ID:** 9842707
- **Project number:** 5P30CA006516-55
- **Recipient organization:** DANA-FARBER CANCER INST
- **Principal Investigator:** BRUCE E. JOHNSON
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $70,961
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9842707

## Citation

> US National Institutes of Health, RePORTER application 9842707, Program 34: Lung Cancer (5P30CA006516-55). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9842707. Licensed CC0.

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