# Center for Molecular Epidemiology

> **NIH NIH P20** · DARTMOUTH COLLEGE · 2020 · $2,255,242

## Abstract

OVERALL ABSTRACT
Establishing the Center for Molecular Epidemiology, Center for Biomedical Research Excellence (COBRE) has
transformed research in the field of molecular epidemiology at Dartmouth. As the only Center for Molecular
Epidemiology in northern New England, and one of the only COBRE programs nationally with this focus, we
have successfully recruited and mentored early career investigators who are now becoming independent in
their careers. They represent the new generation of investigators in this emerging area of research both
regionally and nationally. In doing so, we have expanded our research productivity and grant portfolio, as
evidenced by a growing number of publications and grants awarded. In addition to their independent grant
submissions, our tight-knit group of investigators catalyzed a number of major initiatives and interdisciplinary
grant opportunities by leveraging Center resources. These achievements include creating a Department of
Epidemiology, increasing program and center award support, and attaining innovative cross-disciplinary
training grants. As part of this Phase II application, we proposed to progress our Center towards sustainability
by further enhancing recruitment, career development, and engagement of talented junior investigators. We
will bring together this enlarging group of diverse faculty with shared interests in integrating and translating
cutting edge scientific technologies and discoveries to improve our understanding of major human health
concerns. Such efforts are crucial for directing clinical decisions, public health policies and practice change.
We will strengthen our vibrant molecular epidemiology research infrastructure from which innovative methods
can be applied and new discoveries can be translated. Specifically, we will add four new independent
research projects with intertwined themes that are supported by our state-of-the-art Biorepository Core created
in Phase I. Through our effective Administrative, Career Development, and Research Integration Core, we will
offer a Pilot Program to incentivize pioneering research and regional partnerships. These essential
components will allow us to achieve our goals of: (1) stimulating rigorous innovative research and fostering the
career development of junior investigators and recruiting new faculty and members to our Center, (2)
promoting translation of novel technologies and basic research findings on common pathways of disease
etiology and progression, and (3) informing strategies to prevent human disease throughout the lifespan. Our
success in Phase I combined with strong institutional support, positions us to serve as a vital resource in
molecular epidemiology for northern New England, COBRE and IDeA Networks of Biomedical Research
Excellence (INBRE) programs regional and nationally, and for cultivating molecular epidemiology more broadly.

## Key facts

- **NIH application ID:** 9843672
- **Project number:** 5P20GM104416-08
- **Recipient organization:** DARTMOUTH COLLEGE
- **Principal Investigator:** MARGARET Rita KARAGAS
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $2,255,242
- **Award type:** 5
- **Project period:** 2013-03-01 → 2023-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9843672

## Citation

> US National Institutes of Health, RePORTER application 9843672, Center for Molecular Epidemiology (5P20GM104416-08). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9843672. Licensed CC0.

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