# Biospecimen Services Shared Resource

> **NIH NIH P30** · OHIO STATE UNIVERSITY · 2020 · $192,701

## Abstract

CORE-003: BIOSPECIMEN SERVICES SHARED RESOURCE (BSSR)
PROJECT SUMMARY / ABSTRACT
The OSUCCC Biospecimen Services Shared Resource (BSSR) is a longstanding SR whose broad mission is
to provide high quality biospecimen procurement, processing, storage and distribution to OSUCCC
researchers. The BSSR is directed by Ms. Heather Hampel, who also is the OSUCCC Associate Director for
Biospecimen Science. The BSSR is comprised of two arms: the first arm is for collection using a universal
consenting and biobanking protocol that has been substantially modified and that was IRB-approved one year
ago. It is modeled and named after the existing Total Cancer Care (TCC) protocol in place at Moffitt Cancer
Center. The TCC protocol includes a broad informed consent allowing for access to pathologic and clinical
data for life, with the ability to re-contact patients for clinical follow up and/or to offer participation in other
clinical trials for which they are eligible. The collected tissues are stored at the BSSR biobank, located at
OSU's Nationwide Children's Hospital Biopathology Center, which is both NCI funded and approved by the
College of American Pathologists. During the first 11 months of the TCC protocol consenting process, 6,494
cancer patients have been consented, representing a 90% accrual rate for contacted subjects. There are
24,346 aliquots collected, and 2,050 paraffin-embedded tissues are available.
The second arm of the BSSR provides prospectively procured biospecimens to OSUCCC investigators from all
five OSUCCC research programs who are in need of pathology samples. The decision to distribute BSSR
tissues is decided by committee who evaluates scientific merit, source of funding and availability. Researchers
may receive samples and data with subject identifiers with prior IRB-approval, or de-identified and coded-
limited data sets without additional prior IRB approvals. Over the past five-year period, the BSSR has provided
56 OSUCCC investigators with 17,617 prospectively-procured samples from 4317 subjects among 73 IRB
protocols, and has contributed to 88 publications, including 8 in journals with an impact factor >10. Also, the
BSSR provided services for prospective procurement to 2 SPORES, 10 R01s, 4 R21s, 3 U01s, 3 P01s, 2 K
awards, and a T32.
Future plans for BSSR are to complete the implementation of the TCC protocol in all of the OSUCCC's
Disease Specific Research Groups, to reduce the number of IRB-approved banking protocols across the
OSUCCC, to establish web-based consenting and electronic patient questionnaires, and to develop
collaborative relationships with other NCI-designated CCC's for data sharing and enhancement of research.
The BSSR leverages extensive institutional support and seeks only 9.3% support from CCSG funds.
Biospecimen Services Shared Resource is part of the Clinical Grouping.

## Key facts

- **NIH application ID:** 9843861
- **Project number:** 5P30CA016058-44
- **Recipient organization:** OHIO STATE UNIVERSITY
- **Principal Investigator:** Heather D Hampel
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $192,701
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9843861

## Citation

> US National Institutes of Health, RePORTER application 9843861, Biospecimen Services Shared Resource (5P30CA016058-44). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9843861. Licensed CC0.

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