# Biostatistics Shared Resource

> **NIH NIH P30** · OHIO STATE UNIVERSITY · 2020 · $275,508

## Abstract

CORE-007: BIOSTATISTICS SHARED RESOURCE (BSR)
PROJECT SUMMARY / ABSTRACT
The Biostatistics Shared Resource (BSR) provides The Ohio State University Comprehensive Cancer Center
(OSUCCC) investigators with a centralized resource for biostatistical expertise. The BSR is directed by Dr.
Soledad Fernandez and the Associate Director is Dr. Kevin Coombes (TT). Statistical issues are addressed at
all levels of investigation, from the design of experiments to the maintenance of data quality, and from
conclusions based on formal hypothesis testing to important leads discovered by data exploration. In support
of this objective, the Specific Aims of this resource are to: 1) collaborate with OSUCCC investigators in all
aspects of biomedical research: design, implementation and discovery; 2) enable strong and consistent
collaborations by providing a biostatistical “navigator” to all OSUCCC programs and disease groups; and 3)
provide biostatistical and methodological review of all cancer protocols submitted to the Clinical Scientific
Review Committee (CSRC) and the Data Safety Monitoring Committee (DSMC), and to provide support to the
Biospecimen Services Shared Resource and its Total Cancer Care protocol. Over the past five years, the BSR
has increased its integration and collaborations with all OSUCCC programs. The main highlights of BSR
activities during the last funding period include: 1) BSR biostatisticians supported 254 cancer-related papers
and 14 of these had a journal impact factor >10. These metrics represent a 33% increase in number of
publications since our last grant. 2) BSR members received support from 11 renewed and 3 new programmatic
grants, including the first NCI-funded Thyroid Cancer SPORE and also 36 R01s. 3) BSR hired nine additional
biostatisticians to support OSUCCC investigators, including Dr. Kevin Coombes (TT), former Director of the
Bioinformatics Shared Resource at MD Anderson Cancer Center. Other recruits have enhanced our clinical
trials expertise with Bayesian methodologies. 4) BSR implemented a new biostatistical navigator model to
expand, improve and unify support to OSUCCC investigators while maintaining access to the wide breadth of
expertise with other biostatisticians across different OSU colleges. 5) The BSR increased its interactions with
the Disease Specific Research Groups DSRGs by assigning a dedicated biostatistician to each group. 6) BSR
integrates support with other shared resources, such as Biomedical Informatics Shared Resource, Genomics
Shared Resource, Pharmacoanalytical Shared Resource, Analytical Cytometry Shared Resource and
Behavioral Measurement Shared Resource. 7) BSR members provided education and promoted the benefits
of innovative designs for early phase clinical trials to OSUCCC investigators. The BSR leverages extensive
institutional support, and seeks only 7.7% support from CCSG funds. The Biostatistics Shared Resource is
part of the Quantitative Grouping.

## Key facts

- **NIH application ID:** 9843865
- **Project number:** 5P30CA016058-44
- **Recipient organization:** OHIO STATE UNIVERSITY
- **Principal Investigator:** Soledad A Fernandez
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $275,508
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9843865

## Citation

> US National Institutes of Health, RePORTER application 9843865, Biostatistics Shared Resource (5P30CA016058-44). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9843865. Licensed CC0.

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