# Biomedical Informatics Shared Resource

> **NIH NIH P30** · OHIO STATE UNIVERSITY · 2020 · $121,599

## Abstract

CORE-008 – BIOMEDICAL INFORMATICS SHARED RESOURCE (BISR)
PROJECT SUMMARY / ABSTRACT
The OSUCCC Biomedical Informatics Shared Resource (BISR) provides a comprehensive suite of services,
technologies and expertise that collectively support the resource-efficient conduct of basic, clinical/translational
and population science for OSUCCC investigators. The Specific Aims of the BISR are: 1) to provide state-of-
the-art bioinformatics and computational biology services for the analysis of massively parallel sequence data
and the analysis of microarray datasets; 2) to provide OSUCCC investigators with services, expertise and
access to technology platforms in support of heterogeneous and multi-dimensional biomedical data
management requirements., The BISR, directed by Drs. Jeff Parvin (Aim 1) and Philip Payne (Aim 2), is
supported through a combination of CCSG and project-specific grant funds (via charge-back mechanisms), as
well as significant and ongoing institutional commitments of human, computational, and financial resources.
During the prior five year grant period, the BISR was used by 45 OSUCCC members (59% of total users), but
they accounted for 95.7% of usage. The BISR contributed to 195 publications, 29 with a journal impact factor
greater than 10 and supported 21 NCI grants through billable services (charegebacks) (1 K12, 1 K24, 4 P01s,
2 P50s, 7 R01s, 1 R21, 1 R37, 1 RC2, 1 U01, 1 U10, and 1 U54). This is in addition to 18 BISR (Aim 1) staff
members who have had directly funded appointments on NCI grants (i.e., 3 P01s, 2 P50s, 8 R01s, 1 R21, 1
RC2, 4 U01s, and 1 U54), other grants, and/or OSUCCC institutional funding sources. Through this work,
BISR supported investigators from all five of the OSUCCC research programs. The BISR works closely and
coordinates services with other OSUCCC shared resources, namely the Behavioral Measurement Shared
Resource, the Genomics Shared Resource, the Biostatistics Shared Resource and the Biospecimen Services
Shared Resource with its Total Care Cancer protocol. The future plans of the BISR are to streamline and
strengthen existing next generation sequencing (NGS) data analysis pipelines through integration of new
commercial programs, establish novel data visualization and visual analytics platforms, enhance the OSUCCC
researchers abilities to access clinical data through an OSUCCC Information Warehouse serving as the honest
broker and employing innovative electronic data capture tools, and fully implementing the Total Cancer Care
protocol integration with other cancer centers for real time access to larger sets of electronic health records
linked to biospecimens. The BISR leverages extensive institutional support and seeks only 7.0% support from
CCSG funds. The Biomedical Informatics Shared Resource is part of the Analytics Grouping.

## Key facts

- **NIH application ID:** 9843867
- **Project number:** 5P30CA016058-44
- **Recipient organization:** OHIO STATE UNIVERSITY
- **Principal Investigator:** JEFFREY D PARVIN
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $121,599
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9843867

## Citation

> US National Institutes of Health, RePORTER application 9843867, Biomedical Informatics Shared Resource (5P30CA016058-44). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9843867. Licensed CC0.

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