# Early Phase Clinical Research Support (Core 019)

> **NIH NIH P30** · OHIO STATE UNIVERSITY · 2020 · $221,779

## Abstract

CORE-019: EARLY PHASE CLINICAL RESEARCH SUPPORT (EPCRS) 
PROJECT SUMMARY / ABSTRACT 
A major area of institutional support for clinical cancer research is for investigator-initiated trials. The arrival of 
new investigators into the OSUCCC, the increased attention paid to translational research and changes in the 
funding landscape of clinical trials requires that there be a mechanism for funding investigator initiated studies 
of novel agents and/or novel design. The support of innovative Phase I trials and pilot studies was previously 
supported by the CCSG-mandated Protocol Specific Research Support mechanism. With the recent changes 
in the CCSG guidelines, the Early Phase Clinical Research Support (EPCRS) mechanism has been employed 
since late 2013 as a means of stimulating the conduct of early phase, investigator-initiated studies. The 
EPCRS process is overseen by Dr. William Carson, the Associate Director for Clinical Research (ADCR). 
Investigators are informed of this OSUCCC support mechanism via official communications from OSUCCC 
administration and the Disease Specific Research Group (DSRG) leaders. There is a formal application 
process which is conducted quarterly. Proposals are reviewed by a panel, chaired by the ADCR, Dr. William 
Carson. Successful applications are selected for CCSG support in the form of research nurse or data 
management assistance from the CCC supported Clinical Trials Office (CTO). On average 1-3 studies have 
been approved for support each quarter. In the current funding cycle, a total of 13 studies have been 
supported by the EPCRS and have accrued a total of 175 patients in the last year. In addition, to EPCRS, the 
OSUCCC has a formal, peer-reviewed mechanism, called the Intramural Research Program (IRP), to channel 
developmental funds from Pelotonia, our annual bicycle fundraising event, into bench to beside research.

## Key facts

- **NIH application ID:** 9843880
- **Project number:** 5P30CA016058-44
- **Recipient organization:** OHIO STATE UNIVERSITY
- **Principal Investigator:** Steven M. DeVine
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $221,779
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9843880

## Citation

> US National Institutes of Health, RePORTER application 9843880, Early Phase Clinical Research Support (Core 019) (5P30CA016058-44). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9843880. Licensed CC0.

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