# Bioinformatics Shared Resource

> **NIH NIH P30** · WAKE FOREST UNIVERSITY HEALTH SCIENCES · 2020 · $329,372

## Abstract

BIOSTATISTICS AND BIOINFORMATICS SHARED RESOURCE 
Project Summary 
The primary goal of the Biostatistics and Bioinformatics Shared Resource (BBSR) is to facilitate the peer- 
reviewed research of Wake Forest Baptist Comprehensive Cancer Center (WFBCCC) members. The BBSR 
collaborates with members from all four scientific Programs throughout all phases of cancer-related research 
projects. Major responsibilities are assumed for methodological, statistical, bioinformatics, and computational 
issues, including study design, sampling, statistical aspects of clinical trial monitoring, interim reviews, and final 
analysis. The BBSR supports the following five areas: 1) Clinical Protocol Development, including development 
of appropriate statistical designs, preparing statistical sections, and reviewing the statistical content of all 
protocols submitted for review at the WFBCCC; 2) Clinical Protocol Monitoring and Analyses, including 
monitoring patient accrual, providing support for quality assurance efforts, and performing interim (when 
needed) and final analyses; 3) Statistical Design and Data Analysis in Support of Grant Development and 
Publications, which includes collaborations with WFBCCC investigators from all Programs to provide guidance 
and support in all stages of research studies and grants. This aspect of service involves meeting with 
WFBCCC investigators to discuss the design and analysis plans for potential grants, conducting regular 
planning sessions with WFBCCC investigators about potential grants, performing statistical analyses of data 
and providing interpretations of results as parts of presentations, abstracts, and publications; 4) Informatics 
Services to WFBCCC investigators from all Programs, including genomics data processing, bioinformatics 
analyses, data annotation and visualization/sharing to support basic, translational and clinical cancer research 
by leveraging the institutionally-maintained Translational Data Warehouse; and 5) Leadership, Education, and 
Training, including participation in graduate-level courses, T32 training grants, mentoring teams for K 
awardees and other young investigators, membership/leadership on committees responsible for scientific and 
administrative decisions for the WFBCCC, and coordination of a monthly seminar series and short courses on 
statistical and/or bioinformatics methods for WFBCCC members. 
The BBSR is co-directed by Ralph D’Agostino, Jr., Ph.D., and Xiaobo Zhou, Ph.D., and is a highly utilized and 
cost-efficient Resource for the WFBCCC. From November 1, 2014 through October 31, 2015, the BBSR 
provided over 5,000 hours of support for cancer-related work and assisted 105 investigators (90 WFBCCC 
Members) from all four WFBCCC Programs while receiving approximately 1.9 FTEs of financial support from 
the Cancer Center Support Grant (with additional support provided by WFBCCC institutional dollars). In 
addition, during the reporting year the BBSR provided statistical suppor...

## Key facts

- **NIH application ID:** 9848530
- **Project number:** 5P30CA012197-45
- **Recipient organization:** WAKE FOREST UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** Wei Zhang
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $329,372
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9848530

## Citation

> US National Institutes of Health, RePORTER application 9848530, Bioinformatics Shared Resource (5P30CA012197-45). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9848530. Licensed CC0.

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