# Cancer Genomics Shared Resource

> **NIH NIH P30** · WAKE FOREST UNIVERSITY HEALTH SCIENCES · 2020 · $125,209

## Abstract

CANCER GENOMICS SHARED RESOURCE 
Project Summary 
Next-generation sequencing (NGS) and microarray technologies are essential resources for investigating the 
genomic and molecular underpinnings of cancer formation, progression, and clinical outcomes. The primary 
objective of the Cancer Genomics Shared Resource (CGSR) is to maximize the scientific and clinical impact of 
research by Wake Forest Baptist Comprehensive Cancer Center (WFBCCC) members. This is accomplished 
by providing rapid and cost-effective access to state-of-the-art genomic technologies, while creating a unifying 
environment that cultivates scientific awareness, education, and collaboration. The CGSR supports the 
WFBCCC's mission by providing cancer-prioritized access to comprehensive microarray and NGS 
technologies and offers seamless data flow through to the Biostatistics and Bioinformatics Shared Resource - 
for bioinformatics support. In October 2014, at the instigation of Director Pasche, the former Microarray Core 
Laboratory (2002-2014; which received a score of “excellent” in the prior critique) was renamed the Cancer 
Genomics Shared Resource to reflect the integration of the WFBCCC's microarray core competencies with the 
NGS expertise of the Center for Genomics and Personalized Medicine Research. This new joint-Center 
partnership reflects the strategic plans of the WFBCCC and the Wake Forest School of Medicine (WFSOM), as 
well as supporting priority recommendations of the WFSOM Centers and Cores Advisory Committee. The 
CGSR provides cutting-edge genomic services, prioritizes cancer-specific research, creates an optimal 
environment for the Institution's rapidly developing precision medicine initiative, and seamlessly integrates with 
other key Shared Resources within the WFBCCC to promote integrated, high-quality workflows for cancer 
genomics research. The CGSR is led by Co-Directors Lance Miller, Ph.D., and Greg Hawkins, Ph.D., who 
have established records in cancer genomics research, and is operated by four experienced technicians (two 
at 100% effort, one at 50% effort and one at 5% effort). A bioinformatician devotes 30% of effort to CGSR daily 
operations. In the most recent grant year (11/01/14-10/31/15), the CGSR operated at 80-90% FTE utilization to 
provide 1,144 services to 20 investigators, 75% of which were WFBCCC investigators. Compared to previous 
years, the CGSR doubled its service output and increased its cancer-specific service output by approximately 
50%. The CGSR directly contributes to the scientific achievements of WFBCCC investigators by generating 
high-quality and cost-effective data that will translate into new discoveries, publications, grant awards, and 
grant applications. Further development of CGSR's role in supporting the development and productivity of 
WFBCCC Disease-Oriented Teams and the continued development of seamless workflows across Shared 
Resources are expected to enhance translational genomics initiatives at the WFBC...

## Key facts

- **NIH application ID:** 9848531
- **Project number:** 5P30CA012197-45
- **Recipient organization:** WAKE FOREST UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** Lance David Miller
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $125,209
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9848531

## Citation

> US National Institutes of Health, RePORTER application 9848531, Cancer Genomics Shared Resource (5P30CA012197-45). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9848531. Licensed CC0.

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