# Maintenance of an SPF Macaque Breeding Colony for AIDS Research

> **NIH NIH U42** · TULANE UNIVERSITY OF LOUISIANA · 2020 · $1,348,382

## Abstract

Project Summary
The objective of this application is to request funds for continued support and
maintenance of the U42 supported SPF Indian-origin rhesus monkey breeding colony at
the TNPRC. During the current funding period the colony has been maintained at a
level of approximately 800 animals. This was a management decision based on the
demand from NIH funded AIDS researchers and available funds to support the colony.
Going forward we expect to expand production in the next few years based on recent
developments in funding and animal demand. The specific aims address the
components specified in the funding opportunity announcement (FOA) and are divided
into the overall program description, husbandry core, viral testing core and
genetics/MHC core. Program income (and Center funds) will be used to fund
components of the program not covered by grant funds including: per diem for any
colony animals in excess of the 800 supported by this application, testing for those
animals, infrastructure repairs and improvements, veterinary support for all of the U42
colony animals, behavioral management support, and portions of the genetic testing for
the entire U42 colony.
Specific Aims:
· Overall. To maintain the existing SPF colony and distribute available animals to
 the NIH funded AIDS research community.
· Husbandry and Management. To provide husbandry and veterinary care for the
 SPF breeding colony established in the existing U42 grant. This includes a
 robust program for clinical veterinary medical care and behavioral management.
 The colony has reached a mature self sustaining status with ideal demographics
 to produce up to 150 animals available for assignment each year. Program
 Income generated by the sale of animals will be returned to an account for use
 in supporting the aims of the grant.
· Viral Testing. To assure the SPF status of the colony through continued viral
 testing of existing breeding colony animals and all offspring. Expand
 characterization of the colony beyond the required 4 viruses to include agents
 such as measles virus and Trypanosoma cruzi.
· Genetic/MHC typing . To continue genetic analysis and MHC typing of the
 colony and provide expanded genetic characterization through enhanced
techniques.

## Key facts

- **NIH application ID:** 9849826
- **Project number:** 5U42OD010568-18
- **Recipient organization:** TULANE UNIVERSITY OF LOUISIANA
- **Principal Investigator:** RUDOLF Paul BOHM
- **Activity code:** U42 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $1,348,382
- **Award type:** 5
- **Project period:** 2001-08-09 → 2021-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9849826

## Citation

> US National Institutes of Health, RePORTER application 9849826, Maintenance of an SPF Macaque Breeding Colony for AIDS Research (5U42OD010568-18). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9849826. Licensed CC0.

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