# Gnotobiotic, Microbiology and Metagenonomics

> **NIH NIH P30** · BOSTON CHILDREN'S HOSPITAL · 2020 · $343,706

## Abstract

The Gnotobiotics, Microbiology and Metagenomics Core (Core D), aims to identify the causal relationships 
between our colonizing microbiota and host health and disease, both in human clinical trials and in animal 
models. 
Core D supports more than 50 groups interested in evaluating mechanisms by which the host's microbiota 
affects health and disease, with particular focus to define functional effects of microbial communities in vivo. 
Our resources include an Intake Unit to handle logistics for sample and data collection, a Molecular Unit for 
sequence-based analyses, Microbiology Unit to analyze primary samples and manipulate isolates for 
functional studies, a Gnotobiotic (germfree) mouse facility for in vivo studies in animal models, and 
Computational Unit which includes bioinformatics and computational support, including access to 
computational clusters and personnel for assisting in experimental design and analysis of complex 
metagenomic datasets. 
As a core we provide support to nearly all academic centers in the greater Boston area.

## Key facts

- **NIH application ID:** 9850249
- **Project number:** 5P30DK034854-35
- **Recipient organization:** BOSTON CHILDREN'S HOSPITAL
- **Principal Investigator:** LYNN BRY
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $343,706
- **Award type:** 5
- **Project period:** — → 2021-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9850249

## Citation

> US National Institutes of Health, RePORTER application 9850249, Gnotobiotic, Microbiology and Metagenonomics (5P30DK034854-35). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9850249. Licensed CC0.

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