# Clinical-Experimental Tissue Resource (ETR)

> **NIH NIH P30** · UNIVERSITY OF CALIFORNIA-IRVINE · 2020 · $114,156

## Abstract

Core 007 - Clinical - Project Summary/Abstract - Experimental Tissue Resource (ETR) 
The primary objective of the Experimental Tissue Shared Resource (ETR) is to provide basic, translational, and 
clinical researchers within the Cancer Center access to, and analysis of, human and animal tissues. A key 
advantage is that this Core leverages the technical and professional expertise of the Department of Pathology 
and Laboratory Medicine. Four service lines are currently offered: 1) Tissue Procurement and Interpretive 
Histopathology Consultation, 2) Tissue Histology and IHC services, 3) Laser Capture microdissection, and 4) 
Mouse Pathology services. In the prior full funding period, 69 CFCCC Members have used ETR services, an 
increase of 10% over the prior 5-year funding period. Fifteen clients have been provided letters of collaboration for 
cancer-focused grant proposals, and 6 junior faculty members have been mentored with regard to developing tissue 
procurement or analysis aims in grant proposals. The histology component has provided high-quality service at 
below-market recharge rates, with short turn-around times for CFCCC members who are mainly pursuing 
translational research on human cancer specimens or studying animal models of human cancer. These 
features have made our histology services superior to those available from commercial vendors, contributing to 
usage growth. ETR services contributed to 58 publications in the previous 5 years, from 36 different CFCCC 
Principal Investigators. Interpretive histopathology services have been particularly valuable to investigators 
pursuing translational and clinical research projects. In the coming funding period, priorities for growing the 
service include updating the IRB and prospective informed consent process for tissue banking, adding 
cryostorage space and specimen processing capabilities for bone marrow aspirate collection, and 
implementing new data management tools for the intake, inventory, QC/QA, and disbursement of research 
tissues.

## Key facts

- **NIH application ID:** 9851361
- **Project number:** 5P30CA062203-23
- **Recipient organization:** UNIVERSITY OF CALIFORNIA-IRVINE
- **Principal Investigator:** ROBERT Andrew EDWARDS
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $114,156
- **Award type:** 5
- **Project period:** — → 2022-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9851361

## Citation

> US National Institutes of Health, RePORTER application 9851361, Clinical-Experimental Tissue Resource (ETR) (5P30CA062203-23). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9851361. Licensed CC0.

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