# Biometric Genetic Analysis of CardiopulmonaryDisease

> **NIH NIH T32** · CASE WESTERN RESERVE UNIVERSITY · 2020 · $296,362

## Abstract

This renewal training program will continue to train next generation of scientists in the
areas of statistical genetic analysis, genetic epidemiology, and bioinformatics, with emphasis
placed on advancing research in the area of cardiopulmonary and cardiovascular disease.
Specifically, the first goal is to lay a solid foundation for the trainees in understanding
epidemiology/genetic epidemiology, biostatistics and bioinformatics. We have designed a unique
course curriculum for the trainees that maintains a focus on statistical genetics/bioinformatics
while allowing flexibility in the remainder of their PhD training. The second goal is to provide
training in implementing and developing methods of analysis, with a particular focus on their
application to cardiopulmonary diseases. We will accomplish these goals using a co-mentoring
system, with the primary mentor focused on developing and extending analysis methods and the
co-mentor(s) providing domain expertise for the cardiopulmonary application of those methods.
Multiple didactic and practical exposures, formal and informal mentoring, communication with
internationally known biostatisticians/geneticists/cardiopulmonary epidemiologists, and training in
the responsible conduct of research, will all be incorporated into the training program. Particularly,
significant changes have been made in this renewal application. 1) New leadership has been
established. 2) Only predoctoral students will be trained, to focus on our modernized predoctoral
program that has produced many highly successful academics. 3) We expand training in
bioinformatics, since Big Data is gaining importance in genomic and translational research. 4) A
significant number of new training faculty who are well funded, have diverse areas of expertise,
and have abundant training experience in both methodological and content areas have been
recruited. 5) Strict evaluation and career mentoring plans will be applied to further improve the
training quality. 6) Junior mentors will bring new cutting-edge research, with a junior mentor
training plan in place. 7) A new recruitment plan of URM has been developed. We thus believe
the BGACD program will continue its success in training biomedical scientists, in particular to help
understand the etiology of cardiopulmonary disease.

## Key facts

- **NIH application ID:** 9852608
- **Project number:** 5T32HL007567-35
- **Recipient organization:** CASE WESTERN RESERVE UNIVERSITY
- **Principal Investigator:** XIAOFENG ZHU
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $296,362
- **Award type:** 5
- **Project period:** 1994-07-01 → 2022-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9852608

## Citation

> US National Institutes of Health, RePORTER application 9852608, Biometric Genetic Analysis of CardiopulmonaryDisease (5T32HL007567-35). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9852608. Licensed CC0.

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