# Shared Resource: Proteomics & Metabolomics

> **NIH NIH P30** · FRED HUTCHINSON CANCER RESEARCH CENTER · 2020 · $395,455

## Abstract

PROJECT SUMMARY: PROTEOMICS & METABOLOMICS SHARED RESOURCE (P&MSR)
The Proteomics and Metabolomics Shared Resource (P&MSR) consists of the Fred Hutch (FH)-based
Proteomics Facility and the University of Washington South Lake Union (UW-SLU) Metabolomics Facility. The
P&MSR Proteomics Facility was formed in 2002 and has been under the direction of Dr. Phil Gafken since its
inception. The P&MSR Metabolomics Facility was formed in 2013 and has been under the direction of Dr.
Daniel Raftery. The mission of the P&MSR is (1) to provide high-quality, cost-effective, and reliable service in a
timely manner for proteomics and metabolomics experiments; (2) to develop and implement new omics
experiments, assays, and tools to uncover the molecular details influencing cancer biology; and (3) to support
the development of translatable and clinical tests. The P&MSR operates and maintains chromatography, mass
spectrometry, and nuclear magnetic resonance instruments and offers services such as experimental design
and consultation, sample preparation and chromatography, protein or metabolite identification and
quantification, protein modification characterization, targeted protein or metabolite quantification, metabolic flux
analysis, and data analysis and informatics support. New technologies and services are continually being
evaluated based on feedback from Consortium members. Over the next granting period, areas of interest that
will be investigated include the analysis of major histocompatibility complex peptides to support cancer
immunology and immunotherapy research. For metabolomics we will add to our over 20 current assays by
expanding our capabilities to measure metabolic flux, provide the capability to investigate real-time metabolism
studies using stable isotope tracers, and develop higher throughput global profiling assays to support research
in cancer biology. With well-established operation policies, Consortium users have cost-effective, reliable, and
immediate access to the P&MSR. The research supported by the P&MSR demonstrates that it is an important
part of the critical Shared Resources infrastructure needed to support the Fred Hutch/University of Washington
Cancer Consortium.

## Key facts

- **NIH application ID:** 9853650
- **Project number:** 2P30CA015704-45
- **Recipient organization:** FRED HUTCHINSON CANCER RESEARCH CENTER
- **Principal Investigator:** Philip R Gafken
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $395,455
- **Award type:** 2
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9853650

## Citation

> US National Institutes of Health, RePORTER application 9853650, Shared Resource: Proteomics & Metabolomics (2P30CA015704-45). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/9853650. Licensed CC0.

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