# Core C

> **NIH NIH U19** · BETH ISRAEL DEACONESS MEDICAL CENTER · 2020 · $753,572

## Abstract

Infection of rhesus monkeys with simian immunodeficiency virus (SIV) or simian-human immunodeficiency virus
(SHIV) is a key animal model for HIV-1 infection. Nonhuman primates (NHP) are complex, higher order species
that require specialized infrastructure and experienced staff in a research setting. Core C (NHP Core) aims to
support this IPCAVD program by providing all the expertise, infrastructure, reagents, personnel,
animals, and logistics for the conduct of complex in vivo studies in rhesus monkeys. Core C will involve
leadership from Beth Israel Deaconess Medical Center and Bioqual and is well positioned to meet program
objectives. The goal of Core C is to provide leadership and technical expertise to ensure consistency and quality
control in animal selection, execution of study protocols, experimental procedures, sample acquisition and
distribution, and data collection and analysis. To accomplish this goal, we propose three Specific Aims:
Specific Aim 1. To support this IPCAVD program by selecting and providing rhesus monkeys, providing
exceptional animal care, and conducting experimental vaccine studies
Specific Aim 2. To provide facilities for the receipt, cataloging, processing, storage, and distribution of blood
and tissue samples in compliance with Good Clinical Laboratory Practice
Specific Aim 3. To obtain and to maintain all required regulatory approvals for the proposed studies

## Key facts

- **NIH application ID:** 9853726
- **Project number:** 5U19AI128751-03
- **Recipient organization:** BETH ISRAEL DEACONESS MEDICAL CENTER
- **Principal Investigator:** Dan H. Barouch
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $753,572
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9853726

## Citation

> US National Institutes of Health, RePORTER application 9853726, Core C (5U19AI128751-03). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/9853726. Licensed CC0.

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