# Shared Resource-Advanced Biophotonics Core

> **NIH NIH P30** · SALK INSTITUTE FOR BIOLOGICAL STUDIES · 2020 · $309,254

## Abstract

Advanced Biophotonics Core Shared Resource - Project Summary/Abstract 
The Advanced Biophotonics Core (ABC) provides imaging and analysis instrumentation coupled with technical 
and collaborative support staff for advanced light and electron microscopy of biological systems. Cancer 
Center members use the facility for high-throughput imaging assays, high-resolution imaging of live cell and 
tissue dynamics, super-resolution microscopy, large 3D volume imaging of tissues, electron microscopy 
analysis of subcellular morphology and protein distribution, and automated computational image processing, 
visualization, and analysis. The ABC Core is also actively pursuing and developing new cutting-edge imaging 
and analysis methodologies to better serve the needs of Cancer Center researchers, such as cryo-correlative 
light and electron microscopy, light-sheet imaging of cleared and expanded tissues, and machine-learning 
based processing, segmentation, and analysis of light and electron microscope images. The ABC Core is 
committed to providing Cancer Center members: 1) access to light and electron microscopes, specialized 
sample preparation reagents and technologies, and computational hardware and software for analysis and 
visualization, 2) free one-on-one training on all microscopes, as well as image processing and analysis 
software, 3) consulting and collaborative support for experimental design and implementation of imaging and 
analysis experiments, 4) sample preparation for electron microscopy, tissue clearing, and expansion 
microscopy, 5) workshops and demos with advanced microscope and software technologies, 6) weekly open- 
door imaging boot camp on advanced imaging and image processing techniques, and 7) a monthly 
Biophotonics scientific seminar series followed by town-hall style discussions with ABC Core staff and users.

## Key facts

- **NIH application ID:** 9853747
- **Project number:** 5P30CA014195-47
- **Recipient organization:** SALK INSTITUTE FOR BIOLOGICAL STUDIES
- **Principal Investigator:** Axel Nimmerjahn
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $309,254
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9853747

## Citation

> US National Institutes of Health, RePORTER application 9853747, Shared Resource-Advanced Biophotonics Core (5P30CA014195-47). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9853747. Licensed CC0.

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