# Value and mechanisms of home visitation in obesity interventions for low-income children

> **NIH NIH R01** · RUSH UNIVERSITY MEDICAL CENTER · 2020 · $646,829

## Abstract

PROJECT SUMMARY/ABSTRACT
Children from low-income families are more than twice as likely to become obese than those from higher-
income households, which places them at increased risk for obesity-related chronic diseases throughout their
adult lives. Family-based pediatric obesity interventions, particularly those designed for low-income
populations, are increasingly delivered in children’s homes. Home visitation has a number of potential
advantages that could enhance weight loss outcomes relative to delivering treatment in traditional medical and
academic settings. By eliminating the need for transportation and childcare, home visitation may make
treatment more accessible for low-income families, resulting in a higher dosage of intervention received. Home
visitation allows intervention staff to directly observe and address risk factors in the home environment,
potentially enabling them to provide more tailored and potent treatment recommendations. Caregivers may
also be more likely to apply healthy changes in their household when they learn and rehearse new skills in the
environment where they are to be implemented. Research to date has consistently found that home-based
interventions are more effective than low-intensity comparison conditions such as wait-list controls, health
education, and usual medical care. Yet, as the home visitation treatment modality has been confounded with
intervention dosage, intensity, and content in prior studies, there is a lack of empirical evidence to support its
use. The goal of this project is to systematically evaluate the incremental weight loss benefit and cost-
effectiveness of delivering standard family-based treatment for pediatric overweight/obesity in the home setting
vs. traditional medical settings. In a randomized controlled trial involving low-income households, 266 children
ages 6-11 years will be allocated to 12 months of family-based treatment delivered either in their home or at an
urban academic medical center. Both arms will receive the same intervention content and dosage, and differ
only in the location of in-person treatment sessions. Aim 1 is to test the hypothesis that home-based treatment
produces a greater reduction in child adiposity, reflected in 12-month change in BMI z-score. Aim 2 is to
compare the cost-effectiveness of home-based treatment to medical center-based treatment, and calculate the
added cost of the incremental weight loss benefit associated with home visitation. These data will inform efforts
to disseminate home-based interventions for low-income populations by public health agencies and third-party
payers. Aim 3 is to explore specific mechanisms through which home visitation may improve weight loss
outcomes. The results of this trial will have a strong impact on the design of future pediatric overweight/obesity
interventions, as virtually any program could be adapted for delivery in the home setting.

## Key facts

- **NIH application ID:** 9853776
- **Project number:** 5R01DK111358-04
- **Recipient organization:** RUSH UNIVERSITY MEDICAL CENTER
- **Principal Investigator:** Bradley M. Appelhans
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $646,829
- **Award type:** 5
- **Project period:** 2017-02-01 → 2022-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9853776

## Citation

> US National Institutes of Health, RePORTER application 9853776, Value and mechanisms of home visitation in obesity interventions for low-income children (5R01DK111358-04). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9853776. Licensed CC0.

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