# Integrative Molecular Analysis Core

> **NIH NIH P20** · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · 2020 · $489,548

## Abstract

INTEGRATIVE MOLECULAR ANALYSIS CORE – PROJECT SUMMARY
In the rapidly changing field of Metals in Biology and Medicine, research needs are diverse and complex.
Currently, advances in inorganic biochemistry – and its application to biomedical phenomena – require
sophisticated integration of molecular analyses, including the ability to identify and quantitate trace metal
speciation and metal interactions with biomolecular targets. These analyses require highly trained personnel
with specialized expertise and access to advanced high-end equipment, beyond what is typically available in
most individual research laboratories. The Integrative Molecular Analysis Core (IMAC) provides the UNM
Center for Metals in Biology and Medicine investigators with the necessary expertise and tools for a variety of
modern molecular analyses, including ICP-MS, EPR spin-trapping, and quantitative mass spectrometry.
Moreover, the Core provides in-house analyses, supports innovative protocol development, and provides
training to students, fellows, and faculty in the integrated applications associated with the advanced analytical
instrumentation present in the IMAC facility. The Core additionally leverages access to several other existing
on-campus core facilities to enable innovative biomolecular methods, and provides these services at
subsidized pricing. Even more important than access to the technology, the IMAC provides tailored expertise to
investigators to assist in the design of molecular analyses and data interpretation, to optimize use of valuable
biological samples and resources. The facility will be managed by a cadre of specialists with strong
complementary expertise in molecular analysis, research facility administration, training, and mentoring of
junior faculty. The Core equipment is primarily housed in dedicated space in close proximity to most users.
This centralization of resources and knowledge provides consolidated and cost-effective analytical services
and technical expertise to the Center members and users. The Core is organized in three units: Metals
Analytical Chemistry, Oxidative Stress, and Biological Mass Spectrometry. The Specific Aims of this Core are:
1) to create a centralized, state-of-the-art resource that provides expertise, training and instrumentation for
integrative molecular analysis, focused on metal interactions with biological systems; 2) to support the
research objectives of mentored PIs and cultivate a new cohort of COBRE investigators within the Center for
Metals in Biology and Medicine; and 3) develop a user base of established, funded investigators for continued
growth and sustainability of the core facility. The expected outcomes include enhanced multidisciplinary
research capabilities that support metals programs of mentored PIs in their trajectory toward R01 level funding,
and increased collaborations within UNM, and across New Mexico and other IDeA states. These outcomes will
positively impact the level of research excellence...

## Key facts

- **NIH application ID:** 9854029
- **Project number:** 1P20GM130422-01A1
- **Recipient organization:** UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
- **Principal Investigator:** Changjian (Jim) Feng
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $489,548
- **Award type:** 1
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9854029

## Citation

> US National Institutes of Health, RePORTER application 9854029, Integrative Molecular Analysis Core (1P20GM130422-01A1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9854029. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*